{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:49:05Z","timestamp":1761518945543,"version":"3.37.0"},"reference-count":31,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2010,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Eighteen hundred<jats:italic>Neisseria gonorrhoeae<\/jats:italic>isolates collected in Sydney, Australia, in 2007 and 2008 were examined for mosaic<jats:italic>penA<\/jats:italic>alleles that mediated cephalosporin resistance, and the genotypes of the isolates were evaluated. In 2008, there were substantial increases in numbers (from 15 to 85) and proportions (from 1.5 to 10.3%) of mosaic-containing gonococci and major shifts in genotypic patterns, with 10 new genotypes representing 74 of the 85 mosaic-containing isolates and genotypes detected between 2001 and 2005 having disappeared. Enhanced surveillance of gonococcal resistance to cephalosporins is necessary.<\/jats:p>","DOI":"10.1128\/aac.01108-09","type":"journal-article","created":{"date-parts":[[2009,11,17]],"date-time":"2009-11-17T02:57:00Z","timestamp":1258426620000},"page":"554-556","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":24,"title":["Characteristics and Population Dynamics of Mosaic<i>penA<\/i>Allele-Containing<i>Neisseria gonorrhoeae<\/i>Isolates Collected in Sydney, Australia, in 2007-2008"],"prefix":"10.1128","volume":"54","author":[{"given":"John W.","family":"Tapsall","sequence":"first","affiliation":[{"name":"Neisseria Reference Laboratory, Microbiology Department, South Eastern Area Laboratory Services, The Prince of Wales Hospital, Randwick, Sydney, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanghamitra","family":"Ray","sequence":"additional","affiliation":[{"name":"Neisseria Reference Laboratory, Microbiology Department, South Eastern Area Laboratory Services, The Prince of Wales Hospital, Randwick, Sydney, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athena","family":"Limnios","sequence":"additional","affiliation":[{"name":"Neisseria Reference Laboratory, Microbiology Department, South Eastern Area Laboratory Services, The Prince of Wales Hospital, Randwick, Sydney, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.12.3744-3749.2002"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69003-X"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-149-5-200809020-00025"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.1.137-143.2005"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/am.28.1.70-76.1974"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.4.1400-1404.2006"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01604-06"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00198-08"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2004.013805"},{"key":"e_1_3_1_11_2","first-page":"497","volume":"189","year":"2004","unstructured":"Martin, I. M. C., C. A. Ison, D. M. Aanensen, K. A. Fenton, and B. G. Spratt. 2004. Rapid sequence-based identification of gonococcal transmission clusters in a large metropolitan area. J. Infect. Dis.189:497-505.","journal-title":"J. Infect. Dis."},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10156-008-0610-7"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00406-09"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.2.Suppl.S49"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00626-06"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.081721"},{"key":"e_1_3_1_17_2","first-page":"256","volume":"285","year":"2009","unstructured":"Tapsall, J. W. 2009. Implications of current recommendations for third-generation cephalosporin use in the WHO Western Pacific region following the emergence of multi-resistant gonococci. Sex. Transm. Infect.285:256-258.","journal-title":"Sex. Transm. 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