{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T03:28:21Z","timestamp":1772162901304,"version":"3.50.1"},"reference-count":15,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    We compared the efficacy of combination posaconazole-liposomal amphotericin B (LAmB) therapy to monotherapy with either drug in diabetic ketoacidotic or neutropenic mice with disseminated zygomycosis caused by\n                    <jats:italic>Rhizopus oryzae<\/jats:italic>\n                    . Combination therapy was no better than LAmB alone, and posaconazole monotherapy did not improve survival or reduce fungal burden versus placebo.\n                  <\/jats:p>","DOI":"10.1128\/aac.01124-08","type":"journal-article","created":{"date-parts":[[2008,10,20]],"date-time":"2008-10-20T20:44:44Z","timestamp":1224535484000},"page":"772-775","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":90,"title":["Posaconazole Mono- or Combination Therapy for Treatment of Murine Zygomycosis"],"prefix":"10.1128","volume":"53","author":[{"given":"Ashraf S.","family":"Ibrahim","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor\u2014University of California Los Angeles Medical Center, Torrance, California"},{"name":"David Geffen School of Medicine at UCLA, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teclegiorgis","family":"Gebremariam","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor\u2014University of California Los Angeles Medical Center, Torrance, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie A.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Charles River Laboratories, Davis, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"John E.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor\u2014University of California Los Angeles Medical Center, Torrance, California"},{"name":"David Geffen School of Medicine at UCLA, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad","family":"Spellberg","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor\u2014University of California Los Angeles Medical Center, Torrance, California"},{"name":"David Geffen School of Medicine at UCLA, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.11.3647-3650.2003"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.1.126-133.2006"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.10.3343-3344.2003"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.2.721-727.2005"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl350"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI32338"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01458-07"},{"key":"e_1_3_2_9_2","first-page":"524","year":"1992","unstructured":"Kwon-Chung, K. 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