{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T17:14:12Z","timestamp":1782753252896,"version":"3.54.5"},"reference-count":14,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>The combined systemic and topical administration of voriconazole has successfully been used to treat keratomycosis. Because no voriconazole eye drop product is commercially available, we prepared a sterile eye drop solution (10 mg\/ml). Voriconazole remains stable over 30 days, providing an eye drop solution suitable for use for the topical treatment of fungal keratitis.<\/jats:p>","DOI":"10.1128\/aac.01126-08","type":"journal-article","created":{"date-parts":[[2008,11,11]],"date-time":"2008-11-11T01:55:25Z","timestamp":1226368525000},"page":"798-799","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":53,"title":["Preparation and Stability of Voriconazole Eye Drop Solution"],"prefix":"10.1128","volume":"53","author":[{"given":"Antoine","family":"Dupuis","sequence":"first","affiliation":[{"name":"Centre Hospitalier Universitaire de Poitiers, Poitiers, France"},{"name":"Faculte\u0301 de Me\u0301decine et de Pharmacie, Universite\u0301 de Poitiers, Poitiers, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Tournier","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire de Poitiers, Poitiers, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwenae\u0308l","family":"Le Moal","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire de Poitiers, Poitiers, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Venisse","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire de Poitiers, Poitiers, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S1350-9462(97)00002-5","volume":"17","year":"1998","unstructured":"Bourlais, C. L., L. Acar, H. Zia, P. A. Sado, T. Needham, and R. Leverge. 1998. Ophthalmic drug delivery systems\u2014recent advances. Prog. Retin. Eye Res.17:33-58.","journal-title":"Prog. Retin. Eye Res."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2006.07.033"},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S0181-5512(07)92614-5","volume":"30","year":"2007","unstructured":"Ch\u00e9dru-Legros, V., M. Fines-Guyon, A. Ch\u00e9rel, A. Perdriel, F. Albessard, D. Debruyne, and F. Mouriaux. 2007. Fortified antibiotic (vancomycin, amikacin and ceftazidime) eye drop stability assessment at \u221220 degrees C. J. Fr. Ophtalmol.30:807-813.","journal-title":"J. Fr. Ophtalmol."},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/00003226-200207000-00015","volume":"21","year":"2002","unstructured":"D\u00edaz-Valle, D., J. M. Benitez del Castillo, E. Amor, N. Toledano, M. M. Carretero, and T. D\u00edaz-Valle. 2002. Severe keratomycosis secondary to Scedosporium apiospermum. Cornea21:516-518.","journal-title":"Cornea"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0731-7085(98)00004-1"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1D128"},{"key":"e_1_3_2_8_2","first-page":"391","volume":"22","year":"2003","unstructured":"Lai, T. F., R. Malhotra, R. Esmail-Zaden, A. Galanopoulas, M. Chehade, and D. Selva. 2003. Use of voriconazole in Scedosporium apiospermum keratitis. Cornea22:391-392.","journal-title":"Cornea"},{"key":"e_1_3_2_9_2","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1001\/archophthalmol.2007.71","volume":"126","year":"2008","unstructured":"Lau, D., M. Fedinands, L. Leung, R. Fullinfaw, D. Kong, G. Davies, and M. Daniell. 2008. Penetration of voriconazole, 1%, eyedrops into human aqueous humor: a prospective open-label study. Arch. Ophthalmol.126:343-346.","journal-title":"Arch. Ophthalmol."},{"key":"e_1_3_2_10_2","first-page":"238","volume":"56","year":"2008","unstructured":"Mehta, H., H. B. Mehta, P. Garg, and H. Kodial. 2008. Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis. Indian J. Ophthalmol.56:238-240.","journal-title":"Indian J. Ophthalmol."},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200767020-00009"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00762-06"},{"key":"e_1_3_2_13_2","first-page":"1159","volume":"40","year":"1983","unstructured":"Trissel, L. A. 1983. Avoiding common flaws in stability and compatibility studies of injectable drugs. Am. J. Hosp. Pharm.40:1159-1160.","journal-title":"Am. J. Hosp. Pharm."},{"key":"e_1_3_2_14_2","unstructured":"U.S. Pharmacopeial Convention. 1995. Pharmacopeia of the United States of America (the national formulary). U.S. Pharmacopeial Convention Rockville MD."},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200207000-00016"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01126-08","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01126-08","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T19:52:53Z","timestamp":1645473173000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.01126-08"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["10.1128\/AAC.01126-08"],"URL":"https:\/\/doi.org\/10.1128\/aac.01126-08","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2]]},"assertion":[{"value":"2008-08-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-10-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}