{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:47:40Z","timestamp":1761662860224},"reference-count":21,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We determined the\n            <jats:italic>in vitro<\/jats:italic>\n            MIC of arbekacin against 200\n            <jats:italic>Acinetobacter<\/jats:italic>\n            isolates recovered from wounded soldiers. The median MIC was 2 \u03bcg\/ml (range, 0.5 to &gt;64 \u03bcg\/ml). A total of 97.5% of the isolates had arbekacin MICs of &lt;8 \u03bcg\/ml and 86.5% had MICs of \u22644 \u03bcg\/ml. There was no association between the arbekacin MIC and susceptibility to 16 other antibiotics or the specimen source (\n            <jats:italic>P<\/jats:italic>\n            = 0.7239). Synergy testing suggested an enhanced effect of arbekacin-carbapenem combinations.\n          <\/jats:p>","DOI":"10.1128\/aac.01173-09","type":"journal-article","created":{"date-parts":[[2010,4,20]],"date-time":"2010-04-20T03:30:18Z","timestamp":1271734218000},"page":"3015-3017","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":13,"title":["<i>In<\/i>\n            <i>V<\/i>\n            <i>itro<\/i>\n            Activity of the Aminoglycoside Antibiotic Arbekacin against\n            <i>Acinetobacter baumannii-calcoaceticus<\/i>\n            Isolated from War-Wounded Patients at Walter Reed Army Medical Center"],"prefix":"10.1128","volume":"54","author":[{"given":"Michael J.","family":"Zapor","sequence":"first","affiliation":[{"name":"Walter Reed Army Medical Center, Washington, DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Barber","sequence":"additional","affiliation":[{"name":"Infectious Diseases Clinical Research Program, Washington, DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Summers","sequence":"additional","affiliation":[{"name":"Walter Reed Army Medical Center, Washington, DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George H.","family":"Miller","sequence":"additional","affiliation":[{"name":"Achaogen, Inc., South San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee Ann","family":"Feeney","sequence":"additional","affiliation":[{"name":"Achaogen, Inc., South San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynn E.","family":"Eberly","sequence":"additional","affiliation":[{"name":"Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenn","family":"Wortmann","sequence":"additional","affiliation":[{"name":"Walter Reed Army Medical Center, Washington, DC"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/510079"},{"key":"e_1_3_2_3_2","first-page":"182","volume":"17","year":"1980","unstructured":"Chung, M., R. 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D., J. F. Kragh, Jr., J. C. Wenke, J. Macaitis, C. E. Wade, and J. B. Holcombe. 2008. Combat wounds in Operation Iraqi Freedom and Operation Enduring Freedom. J. Trauma64:295-299.","journal-title":"J. Trauma"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00480-05"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1983.047.01.024"},{"key":"e_1_3_2_19_2","unstructured":"Pharmacokinetics of antimicrobial agents: principles methods and applications. 1993"},{"key":"e_1_3_2_20_2","first-page":"282","volume":"62","year":"1982","unstructured":"Umezawa, H., and S. Kondo. 1982. Mechanisms of resistance to aminoglycoside antibiotics, p. 282. In Handbook of experimental pharmacology, vol. 62. Aminoglycoside antibiotics. Springer-Verlag, New York, NY.","journal-title":"Mechanisms of resistance to aminoglycoside antibiotics"},{"key":"e_1_3_2_21_2","first-page":"89","volume":"49","year":"2001","unstructured":"Yasuhiro, S., O. Tikashi, and I. Koichi. 2001. Evaluation of arbekacin and antibacterial agents synergy for MRSA isolated from blood cultures. Jpn. J. Chemother.49:89-94.","journal-title":"Jpn. J. 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