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Current treatment options for<jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">T. gondii<\/jats:named-content>infection are limited and most have drawbacks, including high toxicity and low tolerability. Additionally, no FDA-approved treatments are available for pregnant women, a high-risk population due to transplacental infection. Therefore, the development of novel treatment options is needed. To aid this effort, this review highlights experimental compounds that, at a minimum, demonstrate inhibition of<jats:italic>in vitro<\/jats:italic>growth of<jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">T. gondii<\/jats:named-content>. When available, host cell toxicity and<jats:italic>in vivo<\/jats:italic>data are also discussed. The purpose of this review is to facilitate additional development of anti-<jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Toxoplasma<\/jats:named-content>compounds and potentially to extend our knowledge of the parasite.<\/jats:p>","DOI":"10.1128\/aac.01176-16","type":"journal-article","created":{"date-parts":[[2016,9,7]],"date-time":"2016-09-07T03:03:57Z","timestamp":1473217437000},"page":"7017-7034","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":40,"title":["Review of Experimental Compounds Demonstrating Anti-Toxoplasma Activity"],"prefix":"10.1128","volume":"60","author":[{"given":"Madalyn M.","family":"McFarland","sequence":"first","affiliation":[{"name":"Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sydney 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