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Between November 2021 and April 2022, a total of 132 clinical\n              <jats:italic>A. baumannii<\/jats:italic>\n              isolates were collected from a tertiary hospital in China. Their growth ability and virulence of these isolates were assessed using growth curve analyses and the\n              <jats:italic>Galleria mellonella<\/jats:italic>\n              infection model. The genetic characteristics of the isolates were further examined through whole-genome sequencing. ST1791\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              isolates represented the largest proportion of isolates in our collection and exhibited the highest growth rate and strongest virulence among all sequence types (STs) analyzed. Whole-genome sequences from 14,159 clinical isolates were collected from the National Center for Biotechnology Information database, and only nine ST1791\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              isolates were detected. Comparative genomic analysis revealed that ST1791\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              carried 11 unique genes, 5 of which were located within the capsular polysaccharide synthesis (\n              <jats:italic>cps<\/jats:italic>\n              ) gene cluster. Single nucleotide polymorphisms (SNPs) between ST1791\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              and other isolates were primarily found in the cps gene cluster. Among the other isolates, ST195\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              and ST208\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              exhibited the smallest SNP differences from ST1791\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              , while ST195\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              and ST1486\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              had high homology. The ST1791\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              strain in Anhui, China, displayed significant homology with ST195\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              , ST208\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              , and ST1486\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              isolates. Compared to other isolates in this study, ST1791\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              exhibited strong growth ability and virulence. Therefore, preventing the further spread of ST1791\n              <jats:sup>O<\/jats:sup>\n              \/ST2\n              <jats:sup>P<\/jats:sup>\n              should be a top public health priority.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1128\/aac.01262-24","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T14:06:37Z","timestamp":1733493997000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":8,"title":["Characterization and genomic analysis of the highly virulent\n            <i>Acinetobacter baumannii<\/i>\n            ST1791 strain dominating in Anhui, China"],"prefix":"10.1128","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4679-7839","authenticated-orcid":true,"given":"Zhien","family":"He","sequence":"first","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanhuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cancer Epigenetics Program, The First Affiliated Hospital of University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruobing","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8894-2566","authenticated-orcid":true,"given":"Md Roushan","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, the First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaiwei","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, the First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanying","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences 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