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In a first-in-human, multiple-ascending-dose study, electrocardiogram and pharmacokinetic data were analyzed to assess cardiac repolarization. Placebo-corrected change-from-baseline in QTcF (\u0394\u0394QTcF) ranged from \u221211.4 to +2.4 ms without dose dependency. Concentration\u2013QTc modeling showed a shallow, non-significant slope. 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