{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T16:48:24Z","timestamp":1761929304514},"reference-count":15,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We examined the in vivo activity of tribendimidine against selected trematodes. A single 150-mg\/kg dose of tribendimidine achieved a 99.1% reduction of\n            <jats:italic>Clonorchis sinensis<\/jats:italic>\n            in rats. A 400-mg\/kg dose of tribendimidine reduced\n            <jats:italic>Opisthorchis viverrini<\/jats:italic>\n            in hamsters by 95.7%. High doses of tribendimidine showed no activity against\n            <jats:italic>Schistosoma mansoni<\/jats:italic>\n            and\n            <jats:italic>Fasciola hepatica<\/jats:italic>\n            .\n          <\/jats:p>","DOI":"10.1128\/aac.01366-06","type":"journal-article","created":{"date-parts":[[2006,12,29]],"date-time":"2006-12-29T01:39:36Z","timestamp":1167356376000},"page":"1096-1098","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":53,"title":["Evaluation of the In Vivo Activity of Tribendimidine against\n            <i>Schistosoma mansoni<\/i>\n            ,\n            <i>Fasciola hepatica<\/i>\n            ,\n            <i>Clonorchis sinensis<\/i>\n            , and\n            <i>Opisthorchis viverrini<\/i>"],"prefix":"10.1128","volume":"51","author":[{"given":"Jennifer","family":"Keiser","sequence":"first","affiliation":[{"name":"Swiss Tropical Institute, P.O. Box, CH-4002 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Shu-Hua","sequence":"additional","affiliation":[{"name":"National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Chollet","sequence":"additional","affiliation":[{"name":"Swiss Tropical Institute, P.O. Box, CH-4002 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcel","family":"Tanner","sequence":"additional","affiliation":[{"name":"Swiss Tropical Institute, P.O. Box, CH-4002 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju\u0308rg","family":"Utzinger","sequence":"additional","affiliation":[{"name":"Swiss Tropical Institute, P.O. 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