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We propose a new approach to the\n            <jats:italic>in vitro<\/jats:italic>\n            determination of MSWs, along with novel parameters: MPC-D, MSW-D (for dominant mutants, i.e., selected with a high frequency, without a fitness loss), and MPC-F, MSW-F (for inferior mutants, i.e., with an impaired fitness).\n          <\/jats:p>","DOI":"10.1128\/aac.01373-22","type":"journal-article","created":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T14:02:57Z","timestamp":1680789777000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":25,"title":["Mutant Prevention Concentration, Frequency of Spontaneous Mutant Selection, and Mutant Selection Window\u2014a New Approach to the\n            <i>In Vitro<\/i>\n            Determination of the Antimicrobial Potency of Compounds"],"prefix":"10.1128","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4963-9521","authenticated-orcid":false,"given":"Joanna","family":"Krajewska","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Microbiology and Bioanalysis, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3352-038X","authenticated-orcid":false,"given":"Stefan","family":"Tyski","sequence":"additional","affiliation":[{"name":"Department of Antibiotics and Microbiology, National Medicines Institute, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5989-4462","authenticated-orcid":true,"given":"Agnieszka E.","family":"Laudy","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Microbiology and Bioanalysis, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","unstructured":"WHO. 2022. 2021 Antibacterial agents in clinical and preclinical development: an overview and analysis. 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