{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T12:55:44Z","timestamp":1780491344807,"version":"3.54.1"},"reference-count":38,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T00:00:00Z","timestamp":1585008000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/AuthorWarrantyLicense.v1"},{"start":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T00:00:00Z","timestamp":1585008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Malaria Modelling Consortium","award":["UWSC9757"],"award-info":[{"award-number":["UWSC9757"]}]},{"name":"U.S Presidents Malaria Initiative"},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["1032350"],"award-info":[{"award-number":["1032350"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"UK Research and Innovation | Medical Research Council","doi-asserted-by":"publisher","award":["G1100522"],"award-info":[{"award-number":["G1100522"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"UK Research and Innovation | Medical Research Council","doi-asserted-by":"publisher","award":["MR\/L022508\/1"],"award-info":[{"award-number":["MR\/L022508\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2020,3,24]]},"abstract":"<jats:p>Antimalarial drugs have long half-lives, so clinical trials to monitor their efficacy require long periods of follow-up to capture drug failure that may become patent only weeks after treatment. Reinfections often occur during follow-up, so robust methods of distinguishing drug failures (recrudescence) from emerging new infections are needed to produce accurate failure rate estimates. Molecular correction aims to achieve this by comparing the genotype of a patient\u2019s pretreatment (initial) blood sample with that of any infection that occurs during follow-up, with matching genotypes indicating drug failure.<\/jats:p>","DOI":"10.1128\/aac.01517-19","type":"journal-article","created":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T13:15:08Z","timestamp":1579007708000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":20,"title":["A Computer Modelling Approach To Evaluate the Accuracy of Microsatellite Markers for Classification of Recurrent Infections during Routine Monitoring of Antimalarial Drug Efficacy"],"prefix":"10.1128","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5084-527X","authenticated-orcid":false,"given":"Sam","family":"Jones","sequence":"first","affiliation":[{"name":"Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mateusz","family":"Plucinski","sequence":"additional","affiliation":[{"name":"Malaria Branch and U.S. President\u2019s Malaria Initiative, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Kay","sequence":"additional","affiliation":[{"name":"Metrum Research Group, Tariffville, Connecticut, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva Maria","family":"Hodel","sequence":"additional","affiliation":[{"name":"Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian M.","family":"Hastings","sequence":"additional","affiliation":[{"name":"Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","volume-title":"Methods for surveillance of antimalarial drug efficacy","author":"World Health Organization","year":"2009","unstructured":"World Health Organization. 2009. Methods for surveillance of antimalarial drug efficacy. World Health Organization, Geneva, Switzerland."},{"key":"e_1_3_3_3_2","volume-title":"Global technical strategy for malaria 2016\u20132030","author":"World Health Organization","year":"2016","unstructured":"World Health Organization. 2016. Global technical strategy for malaria 2016\u20132030. World Health Organization, Geneva, Switzerland."},{"key":"e_1_3_3_4_2","volume-title":"Methods and techniques for clinical trials on antimalarial drug efficacy: Genotyping to identify parasite populations","author":"World Health Organization","year":"2008","unstructured":"World Health Organization. 2008. Methods and techniques for clinical trials on antimalarial drug efficacy: Genotyping to identify parasite populations. World Health Organization, Geneva, Switzerland."},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2006.75.836"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2005.73.210"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00159-07"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182099004552"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01892-17"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-018-1174-9"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofu059"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01500-16"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.1.4.241"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0035-9203(01)90175-0"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2009.12.007"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2005.10.013"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063433"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00072-15"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-018-2290-9"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-017-1712-4"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04181-14"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-13-138"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003151"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01068-18"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.5706"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-016-1473-5"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01712-10"},{"key":"e_1_3_3_28_2","volume-title":"R: a language and environment for statistical computing","author":"R Core Team","year":"2019","unstructured":"R Core Team. 2019. R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. https:\/\/www.R-project.org\/."},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-24277-4"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-019-0748-2"},{"key":"e_1_3_3_31_2","volume-title":"Malaria parasite counting, malaria microscopy standard operating procedure\u2014MM-SOP-09","author":"World Health Organization","year":"2016","unstructured":"World Health Organization. 2016. Malaria parasite counting, malaria microscopy standard operating procedure\u2014MM-SOP-09. World Health Organization, Geneva, Switzerland."},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00903-07"},{"key":"e_1_3_3_33_2","volume-title":"Malaria parasites and other Haemosporidia","author":"Garnham P","year":"1966","unstructured":"Garnham P. 1966. Malaria parasites and other Haemosporidia. Blackwell Scientific Publications Ltd., Oxford, United Kingdom."},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.44.12.3414-3424.2000"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00590-19"},{"key":"e_1_3_3_36_2","doi-asserted-by":"crossref","unstructured":"Siahaan L. 2018. Laboratory diagnostics of malaria. IOP Conf Ser: Earth Environ Sci 125:012090. doi:10.1088\/1755-1315\/125\/1\/012090. 012090","DOI":"10.1088\/1755-1315\/125\/1\/012090"},{"key":"e_1_3_3_37_2","unstructured":"Therneau T. 2015. A package for survival analysis in S version 2.38. https:\/\/CRAN.R-project.org\/package=survival."},{"key":"e_1_3_3_38_2","unstructured":"Alboukadel Kassambara MK. 2018. survminer: drawing survival curves using \u2018ggplot2\u2019. R package version 0.4.3. https:\/\/CRAN.R-project.org\/package=survminer."},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/39.4.561"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01517-19","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01517-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T23:34:18Z","timestamp":1645486458000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.01517-19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,24]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,3,24]]}},"alternative-id":["10.1128\/AAC.01517-19"],"URL":"https:\/\/doi.org\/10.1128\/aac.01517-19","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,24]]},"assertion":[{"value":"2019-07-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01517-19"}}