{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T02:08:44Z","timestamp":1792548524608,"version":"4.5.0"},"reference-count":51,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T00:00:00Z","timestamp":1616025600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","award":["PP00P3_170702"],"award-info":[{"award-number":["PP00P3_170702"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Australian National Health and Medical Research Council","award":["1104975"],"award-info":[{"award-number":["1104975"]}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2021,3,18]]},"abstract":"<jats:p>Ensuring continued success against malaria depends on a pipeline of new antimalarials. Antimalarial drug development utilizes preclinical murine and experimental human malaria infection studies to evaluate drug efficacy.<\/jats:p>","DOI":"10.1128\/aac.01539-20","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T06:33:07Z","timestamp":1612161187000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":6,"title":["Parasite-Host Dynamics throughout Antimalarial Drug Development Stages Complicate the Translation of Parasite Clearance"],"prefix":"10.1128","volume":"65","author":[{"given":"Lydia","family":"Burgert","sequence":"first","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Basel, Switzerland"},{"name":"University of Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8253-8896","authenticated-orcid":true,"given":"Sophie","family":"Zaloumis","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4613-3672","authenticated-orcid":true,"given":"Saber","family":"Dini","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Marquart","sequence":"additional","affiliation":[{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengxing","family":"Cao","sequence":"additional","affiliation":[{"name":"School of Mathematics and Statistics, University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Cherkaoui","sequence":"additional","affiliation":[{"name":"Medicines for Malaria Venture, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Gobeau","sequence":"additional","affiliation":[{"name":"Medicines for Malaria Venture, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6596-9718","authenticated-orcid":true,"given":"James","family":"McCarthy","sequence":"additional","affiliation":[{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A.","family":"Simpson","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0769-9649","authenticated-orcid":true,"given":"J\u00f6rg J.","family":"M\u00f6hrle","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Basel, Switzerland"},{"name":"University of Basel, Basel, Switzerland"},{"name":"Medicines for Malaria Venture, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4972-593X","authenticated-orcid":true,"given":"Melissa A.","family":"Penny","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Basel, Switzerland"},{"name":"University of Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","unstructured":"World Health Organization. 2019. World malaria report 2019. World Health Organization Geneva Switzerland. https:\/\/www.who.int\/publications\/i\/item\/9789241565721."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-016-1675-x"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3138"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0066967"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.6b00144"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002252"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00519-09"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02883-15"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0021914"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12962"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw174"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-016-1511-3"},{"key":"e_1_3_3_14_2","unstructured":"World Health Organization. 2009. Methods for surveillance of antimalarial drug efficacy. World Health Organization Geneva Switzerland. https:\/\/www.who.int\/malaria\/publications\/atoz\/9789241597531\/en\/."},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-017-1731-1"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-61304-8"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1015762108"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00320-5"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b01586"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aad9735"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01896-19"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa368"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-6696-2.00002-3"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2006.07.009"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-09-018069"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1618939114"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiz557"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12697"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-11-303"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1006113108"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01292-18"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01068-18"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.49058"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1086\/656476"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1416"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-06295-9"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1086\/315353"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2019.03.002"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofx169"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir033"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiz247"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02181-19"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01371-19"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.16.6.710"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030949"},{"key":"e_1_3_3_46_2","unstructured":"Stan Development Team. 2020. RStan: the R interface to Stan. https:\/\/cran.r-project.org\/web\/packages\/rstan\/vignettes\/rstan.html."},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1214\/088342307000000014"},{"key":"e_1_3_3_48_2","unstructured":"Stan Development Team. 2018. Stan modeling language users guide and reference manual. 2.18.0. https:\/\/mc-stan.org\/docs\/2_18\/stan-users-guide\/index.html."},{"key":"e_1_3_3_49_2","first-page":"3571","article-title":"Asymptotic equivalence of Bayes cross validation and widely applicable information criterion in singular learning theory","volume":"11","author":"Watanabe S","year":"2010","unstructured":"Watanabe S. 2010. Asymptotic equivalence of Bayes cross validation and widely applicable information criterion in singular learning theory. J Mach Learn Res 11:3571\u20133594.","journal-title":"J Mach Learn Res"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-10-339"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4754(00)00270-6"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.6"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01539-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01539-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T23:36:56Z","timestamp":1645486616000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.01539-20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,18]]},"references-count":51,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,3,18]]}},"alternative-id":["10.1128\/AAC.01539-20"],"URL":"https:\/\/doi.org\/10.1128\/aac.01539-20","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,18]]},"assertion":[{"value":"2020-08-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01539-20"}}