{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:17:38Z","timestamp":1787066258355,"version":"build-2736575974"},"reference-count":12,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Eumycetoma caused by\n                    <jats:italic>Madurella mycetomatis<\/jats:italic>\n                    is treated surgically and with high doses of ketoconazole. Therapeutic responses are poor, and recurrent infections are common. In search of therapeutic alternatives in the treatment of mycetoma, we determined the\n                    <jats:italic>in vitro<\/jats:italic>\n                    susceptibilities of\n                    <jats:italic>M. mycetomatis<\/jats:italic>\n                    isolates against caspofungin, anidulafungin, and micafungin. As a comparator fungus,\n                    <jats:italic>Aspergillus fumigatus<\/jats:italic>\n                    was used. Minimal effective concentrations (MECs) and MICs were assessed and compared to those of ketoconazole.\n                    <jats:italic>M. mycetomatis<\/jats:italic>\n                    isolates were not susceptible to the echinocandins.\n                  <\/jats:p>","DOI":"10.1128\/aac.01546-09","type":"journal-article","created":{"date-parts":[[2010,3,29]],"date-time":"2010-03-29T23:55:06Z","timestamp":1269906906000},"page":"2738-2740","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":44,"title":["<i>Madurella mycetomatis<\/i>\n                    Is Not Susceptible to the Echinocandin Class of Antifungal Agents"],"prefix":"10.1128","volume":"54","author":[{"given":"Wendy W. J.","family":"van de Sande","sequence":"first","affiliation":[{"name":"Erasmus MC, University Medical Center Rotterdam, Department of Medical Microbiology and Infectious Diseases, \u2032s Gravendijkwal 230, 3015 CE Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed H.","family":"Fahal","sequence":"additional","affiliation":[{"name":"Mycetoma Research Centre, University of Khartoum, Khartoum, Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irma A. J. M.","family":"Bakker-Woudenberg","sequence":"additional","affiliation":[{"name":"Erasmus MC, University Medical Center Rotterdam, Department of Medical Microbiology and Infectious Diseases, \u2032s Gravendijkwal 230, 3015 CE Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"van Belkum","sequence":"additional","affiliation":[{"name":"Erasmus MC, University Medical Center Rotterdam, Department of Medical Microbiology and Infectious Diseases, \u2032s Gravendijkwal 230, 3015 CE Rotterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.7.2742-2746.2004"},{"key":"e_1_3_2_3_2","unstructured":"Reference method for broth dilution antifungal susceptibility testing of filamentous fungi. 2002 vol. 22."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01610-05"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00020-09"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.7.2851-2856.2005"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.5.1912-1915.2004"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2007.04.002"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1006\/abio.1997.2162"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.9.4349-4356.2005"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.4.1364-1368.2005"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.3109\/13693780802713497"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e328307c79c"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01546-09","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01546-09","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T15:18:08Z","timestamp":1645456688000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.01546-09"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["10.1128\/AAC.01546-09"],"URL":"https:\/\/doi.org\/10.1128\/aac.01546-09","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6]]},"assertion":[{"value":"2009-11-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-03-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-06-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}