{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T14:18:42Z","timestamp":1785161922260,"version":"3.55.0"},"reference-count":22,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2025,2,13]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:p>\n              A\n              <jats:italic>Stenotrophomonas maltophilia<\/jats:italic>\n              strain positive for the\n              <jats:italic>bla<\/jats:italic>\n              <jats:sub>VIM-1<\/jats:sub>\n              metallo-beta-lactamase gene and resistant to trimethoprim-sulfamethoxazole was unexpectedly isolated from a surveillance rectal swab. The characterization of the strain revealed carriage of a 91 kb integrative and conjugative element (ICE) harboring several resistance determinants [\n              <jats:italic>sul1<\/jats:italic>\n              ,\n              <jats:italic>bla<\/jats:italic>\n              <jats:sub>VIM-1<\/jats:sub>\n              ,\n              <jats:italic>aac(6')-Ib<\/jats:italic>\n              ,\n              <jats:italic>aac(6')-31<\/jats:italic>\n              ,\n              <jats:italic>qacE<\/jats:italic>\n              \u2206\n              <jats:italic>1<\/jats:italic>\n              ,\n              <jats:italic>cld<\/jats:italic>\n              , and\n              <jats:italic>merEDAPTR<\/jats:italic>\n              ], closely related with a group of\n              <jats:italic>clc<\/jats:italic>\n              -type ICEs widespread among\n              <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n              and other pseudomonads. Results highlighted the possible spreading of similar elements to\n              <jats:italic>S. maltophilia<\/jats:italic>\n              , mediating the acquisition of relevant resistances.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1128\/aac.01554-24","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T14:00:42Z","timestamp":1737036042000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Evidence of dissemination of a\n            <i>clc<\/i>\n            -type integrative and conjugative element to\n            <i>Stenotrophomonas maltophilia<\/i>\n            , mediating acquisition of\n            <i>sul1<\/i>\n            and other resistance determinants"],"prefix":"10.1128","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4807-4343","authenticated-orcid":false,"given":"Selene Rebecca","family":"Boncompagni","sequence":"first","affiliation":[{"name":"Department of Experimental and Clinical Medicine, University of Florence","place":["Florence, Italy"]},{"name":"Microbiology and Virology Unit, Careggi University Hospital","place":["Florence, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Riccobono","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnologies, University of Siena","place":["Siena, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8869-8164","authenticated-orcid":true,"given":"Maria Grazia","family":"Cusi","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnologies, University of Siena","place":["Siena, Italy"]},{"name":"Microbiology and Virology Unit, Siena University Hospital","place":["Siena, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5863-5805","authenticated-orcid":true,"given":"Vincenzo","family":"Di Pilato","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences and Integrated Diagnostics, University of Genoa","place":["Genoa, Italy"]},{"name":"Microbiology Unit, IRCCS Ospedale Policlinico San Martino","place":["Genoa, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9386-0434","authenticated-orcid":true,"given":"Gian Maria","family":"Rossolini","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, University of Florence","place":["Florence, Italy"]},{"name":"Microbiology and Virology Unit, Careggi University Hospital","place":["Florence, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00019-11"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(09)70083-0"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/jacamr\/dlac040"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00405-19"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciae403"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-024-00685-4"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1304.061378"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1304.061378"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2010.10.025"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2020.1730178"},{"key":"e_1_3_3_12_2","volume-title":"Susceptibility testing of infectious agents and evaluation of performance of antimicrobial susceptibility test devices","author":"International Organization for Standards","year":"2019","unstructured":"International Organization for Standards. 2019. Part 1: Broth micro-dilution reference method for testing the in vitro activity of antimicrobial agents against rapidly growing aerobic bacteria involved in infectious diseases. In Susceptibility testing of infectious agents and evaluation of performance of antimicrobial susceptibility test devices. Vol. 20776\u20131."},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2019.03.003"},{"key":"e_1_3_3_14_2","unstructured":"EUCAST. 2024. The European committee on antimicrobial susceptibility testing breakpoint tables for interpretation of MICs and zone diameters (EUCAST). Available from: http:\/\/www.eucast.org"},{"key":"e_1_3_3_15_2","volume-title":"CLSI supplement M100","author":"Clinical and Laboratory Standards Institute","year":"2024","unstructured":"Clinical and Laboratory Standards Institute. 2024. Performance standards for antimicrobial testing. In CLSI supplement M100, 34th ed. Clinical and Laboratory Standards Institute, Wayne, PA.","edition":"34"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(21)00268-8"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15123-0"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00866-23"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkae068"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/msphere.00517-23"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/msystems.01384-21"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.928848"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10532-007-9117-7"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aac.01554-24","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aac.01554-24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T15:04:54Z","timestamp":1739459094000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/aac.01554-24"}},"subtitle":[],"editor":[{"given":"Laurent","family":"Poirel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,2,13]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2,13]]}},"alternative-id":["10.1128\/aac.01554-24"],"URL":"https:\/\/doi.org\/10.1128\/aac.01554-24","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,13]]},"assertion":[{"value":"2024-10-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01554-24"}}