{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:34:18Z","timestamp":1791261258099,"version":"4.1.0"},"reference-count":8,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Fifty clinical\n            <jats:italic>Mycoplasma pneumoniae<\/jats:italic>\n            strains were isolated from 370 children with respiratory tract infections. Four strains were susceptible to macrolides, while the other 46 (92%) were macrolide resistant. The molecular mechanism of resistance was shown to be associated with point mutations in 23S rRNA at positions 2063 and 2064.\n          <\/jats:p>","DOI":"10.1128\/aac.01563-08","type":"journal-article","created":{"date-parts":[[2009,3,10]],"date-time":"2009-03-10T01:23:34Z","timestamp":1236648214000},"page":"2158-2159","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":103,"title":["Molecular Mechanisms of Macrolide Resistance in Clinical Isolates of\n            <i>Mycoplasma pneumoniae<\/i>\n            from China"],"prefix":"10.1128","volume":"53","author":[{"given":"Deli","family":"Xin","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuhuang","family":"Mi","sequence":"additional","affiliation":[{"name":"Wuxi Research Institute of Genetics &amp; Cloning Technology, Wuxi, Jiangsu 214026, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Central Hospital of China National Petroleum Corporation, Langfang, Hebei 065000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Qin","sequence":"additional","affiliation":[{"name":"Wuxi Research Institute of Genetics &amp; Cloning Technology, Wuxi, Jiangsu 214026, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianli","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaogeng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaojie","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ancun","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawei","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.12.4624-4630.2004"},{"key":"e_1_3_2_3_2","first-page":"10","volume":"10","year":"2002","unstructured":"Mi, Z. H., and L. Qin. 2002. Molecular detection method of Mycoplasma pathogen. Chin. J. Birth Health Hered.10:10-11.","journal-title":"Chin. J. Birth Health Hered."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.6.2302-2306.2005"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2001.tb01293.x"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01345-07"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00582-08"},{"key":"e_1_3_2_8_2","first-page":"666","volume":"20","year":"2005","unstructured":"Xin, D. L., Z. H. Mi, A. C. Hou, L. Qin, T. L. Wei, J. Li, and X. Han. 2005, Mechanism for erythromycin resistance of Mycoplasma pneumoniae,J. Appl. Clin. Pediatr.20:666-667.","journal-title":"J. Appl. Clin. Pediatr."},{"key":"e_1_3_2_9_2","first-page":"212","volume":"43","year":"2005","unstructured":"Xin, D. L., A. C. Hou, T. L. Wei, J. Li, and H. Q. Ma. 2005. Macrolides resistance of Mycoplasma pneumoniae. Chin. J. Pediatr.43:212.","journal-title":"Chin. J. Pediatr."}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01563-08","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01563-08","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T20:22:03Z","timestamp":1645474923000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.01563-08"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["10.1128\/AAC.01563-08"],"URL":"https:\/\/doi.org\/10.1128\/aac.01563-08","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5]]},"assertion":[{"value":"2008-11-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-02-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}