{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T18:06:03Z","timestamp":1759341963456},"reference-count":19,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2015,12]]},"abstract":"ABSTRACT<\/jats:title>\n \n Triazole prophylaxis has become the norm in patients with hematological malignancies. Breakthrough infections caused by\n Mucorales<\/jats:named-content>\n during triazole prophylaxis remain a challenging problem. We found that preexposure of\n Rhizopus oryzae<\/jats:named-content>\n to antifungal triazoles (fluconazole, voriconazole, posaconazole, and itraconazole) did not modify the\n in vitro<\/jats:italic>\n susceptibility of\n Rhizopus oryzae<\/jats:named-content>\n to posaconazole. In contrast, preexposure of\n Rhizopus<\/jats:named-content>\n to triazoles was associated with the enhanced\n in vitro<\/jats:italic>\n susceptibility of\n R. oryzae<\/jats:named-content>\n to amphotericin B. Preexposure to posaconazole did not alter the virulence of\n R. oryzae<\/jats:named-content>\n in the fly model of mucormycosis.\n <\/jats:p>","DOI":"10.1128\/aac.01583-15","type":"journal-article","created":{"date-parts":[[2015,9,22]],"date-time":"2015-09-22T02:23:49Z","timestamp":1442888629000},"page":"7830-7832","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":11,"title":["Effect of Preexposure to Triazoles on Susceptibility and Virulence of Rhizopus oryzae"],"prefix":"10.1128","volume":"59","author":[{"given":"Anne-Pauline","family":"Bellanger","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, USA"},{"name":"Chrono-Environment UMR 6249 Research Team, Franche-Comt\u00e9 University and Parasitology-Mycology Department, Central University Hospital (CHU), Besan\u00e7on, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathaniel D.","family":"Albert","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell E.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Medical Science and Surgery, University Orsola-Malpighi, Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J.","family":"Walsh","sequence":"additional","affiliation":[{"name":"Transplantation-Oncology Infectious Diseases Program and Departments of Medicine, Pediatrics, and Microbiology and Immunology, Weill Cornell Medical Center, New York, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios P.","family":"Kontoyiannis","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, MD Anderson Cancer Center, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/428780"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.13.78"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis773"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/597615"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02988.x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dku227"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2015.47.1.49"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.4161\/viru.2.4.17074"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/jac\/dkn224","article-title":"Does pre-exposure of Aspergillus fumigatus to voriconazole or posaconazole in vitro affect its virulence and the in vivo activity of subsequent posaconazole or voriconazole, respectively? A study in a fly model of aspergillosis","volume":"62","author":"Lamaris GA","year":"2008","unstructured":"Lamaris GA, Ben-Ami R, Lewis RE, Kontoyiannis DP. 2008. Does pre-exposure of Aspergillus fumigatus to voriconazole or posaconazole in vitro affect its virulence and the in vivo activity of subsequent posaconazole or voriconazole, respectively? A study in a fly model of aspergillosis. J Antimicrob Chemother 62:539\u2013542.","journal-title":"J Antimicrob Chemother"},{"key":"e_1_3_2_11_2","volume-title":"CLSI document M38-A","author":"Clinical and Laboratory Standards Institute","year":"2008","unstructured":"Clinical and Laboratory Standards Institute. 2008. Reference method for broth dilution antifungal susceptibility testing of conidium-forming filamentous fungi; approved standard\u20142nd ed. CLSI document M38-A. Clinical and Laboratory Standards Institute, Wayne, PA.","edition":"2"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.11.3592-3597.2003"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.4.501"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1086\/339946"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.10.3208-3214.2002"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.39.9.1907"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.10.2915-2918.2000"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1086\/506617"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(03)00136-6"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0709578105"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01583-15","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01583-15","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T23:03:07Z","timestamp":1645484587000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.01583-15"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":19,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.1128\/AAC.01583-15"],"URL":"https:\/\/doi.org\/10.1128\/aac.01583-15","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"2015-07-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-09-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-11-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}