{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T13:46:29Z","timestamp":1785851189991,"version":"3.56.0"},"reference-count":31,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["PID2023-152240OB-C21"],"award-info":[{"award-number":["PID2023-152240OB-C21"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2026,8,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                      is an opportunistic pathogen responsible for a wide range of healthcare-associated infections. In a recent work, we identified a novel Major Facilitator Superfamily efflux system in\n                      <jats:italic toggle=\"yes\">Acinetobacter baumannii<\/jats:italic>\n                      , designated SxtPR, which mediates antimicrobial resistance and pathogenicity (M. Gaona, J. Corral, S. Campoy, J. Barb\u00e9, et al, Antimicrob Agents Chemother e0071224, 2024,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/doi.org\/10.1128\/aac.00712-24\" xlink:type=\"simple\">https:\/\/doi.org\/10.1128\/aac.00712-24<\/jats:ext-link>\n                      ). Here, we report the identification and characterization of a homologous system in\n                      <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                      that plays a similar dual role in antimicrobial resistance and virulence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/aac.01644-25","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T15:01:42Z","timestamp":1781794902000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["A newly identified homologous SxtPR efflux system contributes to sulfamethoxazole\/trimethoprim susceptibility and pathogenesis in\n                    <i>Klebsiella pneumoniae<\/i>"],"prefix":"10.1128","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2047-6156","authenticated-orcid":true,"given":"Jordi","family":"Corral","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/052g8jq94","id-type":"ROR","asserted-by":"publisher"}],"name":"Departament de Gen\u00e8tica i de Microbiologia, Facultat de Bioci\u00e8nces, Universitat Aut\u00f2noma de Barcelona","place":["Barcelona, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"P\u00e9rez-Varela","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/052g8jq94","id-type":"ROR","asserted-by":"publisher"}],"name":"Departament de Gen\u00e8tica i de Microbiologia, Facultat de Bioci\u00e8nces, Universitat Aut\u00f2noma de Barcelona","place":["Barcelona, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Gaona","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/052g8jq94","id-type":"ROR","asserted-by":"publisher"}],"name":"Departament de Gen\u00e8tica i de Microbiologia, Facultat de Bioci\u00e8nces, Universitat Aut\u00f2noma de Barcelona","place":["Barcelona, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"Campoy","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/052g8jq94","id-type":"ROR","asserted-by":"publisher"}],"name":"Departament de Gen\u00e8tica i de Microbiologia, Facultat de Bioci\u00e8nces, Universitat Aut\u00f2noma de Barcelona","place":["Barcelona, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Barb\u00e9","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/052g8jq94","id-type":"ROR","asserted-by":"publisher"}],"name":"Departament de 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