{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:53:44Z","timestamp":1762865624426},"reference-count":19,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The\n            <jats:italic>in vitro<\/jats:italic>\n            activity of TR-700 (torezolid) was evaluated against a collection of 660 staphylococcal blood isolates. TR-700 showed excellent activity against all the staphylococci tested. The MIC\n            <jats:sub>50<\/jats:sub>\n            and MIC\n            <jats:sub>90<\/jats:sub>\n            values of TR-700, linezolid, daptomycin, and vancomycin against methicillin-resistant\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            (MRSA) isolates were 0.25 and 0.5, 2 and 4, 0.5 and 0.5, and 1 and 2 \u03bcg\/ml, respectively. TR-700 demonstrated greater\n            <jats:italic>in vitro<\/jats:italic>\n            potency than linezolid against staphylococci, including linezolid-resistant and vancomycin-nonsusceptible strains, and was 32-fold more active than linezolid against the seven\n            <jats:italic>cfr<\/jats:italic>\n            -positive MRSA strains tested.\n          <\/jats:p>","DOI":"10.1128\/aac.01653-09","type":"journal-article","created":{"date-parts":[[2010,2,23]],"date-time":"2010-02-23T03:24:40Z","timestamp":1266895480000},"page":"2212-2215","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":15,"title":["Comparative Activities of TR-700 (Torezolid) against Staphylococcal Blood Isolates Collected in Spain"],"prefix":"10.1128","volume":"54","author":[{"given":"Carmen","family":"Betriu","sequence":"first","affiliation":[{"name":"Servicio de Microbiologi\u0301a Cli\u0301nica, Hospital Cli\u0301nico San Carlos, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gracia","family":"Morales","sequence":"additional","affiliation":[{"name":"Servicio de Microbiologi\u0301a Cli\u0301nica, Hospital Cli\u0301nico San Carlos, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ici\u0301ar","family":"Rodri\u0301guez-Avial","sequence":"additional","affiliation":[{"name":"Servicio de Microbiologi\u0301a Cli\u0301nica, Hospital Cli\u0301nico San Carlos, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Culebras","sequence":"additional","affiliation":[{"name":"Servicio de Microbiologi\u0301a Cli\u0301nica, Hospital Cli\u0301nico San Carlos, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari\u0301a","family":"Go\u0301mez","sequence":"additional","affiliation":[{"name":"Servicio de Microbiologi\u0301a Cli\u0301nica, Hospital Cli\u0301nico San Carlos, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fa\u0301tima","family":"Lo\u0301pez-Fabal","sequence":"additional","affiliation":[{"name":"Servicio de Microbiologi\u0301a Cli\u0301nica, Hospital Cli\u0301nico San Carlos, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan J.","family":"Picazo","sequence":"additional","affiliation":[{"name":"Servicio de Microbiologi\u0301a Cli\u0301nica, Hospital Cli\u0301nico San Carlos, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","unstructured":"Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. 2009 vol. 29"},{"key":"e_1_3_1_3_2","unstructured":"Performance standards for antimicrobial susceptibility testing. 2009 vol. 29"},{"key":"e_1_3_1_4_2","unstructured":"Antimicrob. 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