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Even with prompt treatment with current antifungals, it often results in corneal perforation and blindness. In this report, we observe that the beta-adrenergic antagonist, propranolol, displays antifungal activity against\n                      <jats:italic toggle=\"yes\">Aspergillus<\/jats:italic>\n                      and\n                      <jats:italic toggle=\"yes\">Fusarium<\/jats:italic>\n                      corneal isolates\n                      <jats:italic toggle=\"yes\">in vitr<\/jats:italic>\n                      o and strikingly blocks disease establishment in a murine model of\n                      <jats:italic toggle=\"yes\">Aspergillus fumigatus<\/jats:italic>\n                      keratitis. These findings suggest that beta-blockers have potential as a novel FK treatment.\n                    <\/jats:p>\n                    <jats:sec>\n                      <jats:title>\n                        <jats:bold>CLINICAL TRIALS<\/jats:bold>\n                      <\/jats:title>\n                      <jats:p>\n                        This study is registered with ClinicalTrials.gov as\n                        <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/study\/NCT00997035\" xlink:type=\"simple\">NCT00997035<\/jats:ext-link>\n                        (MUTT Trial).\n                      <\/jats:p>\n                    <\/jats:sec>\n                  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