{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:35:36Z","timestamp":1761896136650},"reference-count":9,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A West Australian methicillin-resistant\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Staphylococcus aureus<\/jats:named-content>\n            strain (WA MRSA-59) was characterized by microarray and sequencing. Its pseudo-staphylococcal cassette chromosome\n            <jats:italic>mec<\/jats:italic>\n            (SCC\n            <jats:italic>mec<\/jats:italic>\n            ) element comprised\n            <jats:italic>dcs<\/jats:italic>\n            ,\n            <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"gen\" xlink:href=\"Q9XB68\">Q9XB68<\/jats:ext-link>\n            -\n            <jats:italic>dcs<\/jats:italic>\n            ,\n            <jats:italic>mvaS<\/jats:italic>\n            -SCC,\n            <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"gen\" xlink:href=\"Q5HJW6\">Q5HJW6<\/jats:ext-link>\n            ,\n            <jats:italic>dru<\/jats:italic>\n            ,\n            <jats:italic>ugpQ<\/jats:italic>\n            ,\n            <jats:italic>ydeM<\/jats:italic>\n            ,\n            <jats:italic>mecA-mecR-mecI<\/jats:italic>\n            , txbi\n            <jats:italic>mecI<\/jats:italic>\n            ,\n            <jats:italic>tnp<\/jats:italic>\n            IS\n            <jats:italic>431<\/jats:italic>\n            ,\n            <jats:italic>copA2-mco<\/jats:italic>\n            (copper resistance),\n            <jats:italic>ydhK<\/jats:italic>\n            ,\n            <jats:italic>arsC-arsB-arsR<\/jats:italic>\n            (arsenic resistance), open reading frame PT43, and\n            <jats:italic>per-2<\/jats:italic>\n            . Recombinase genes,\n            <jats:italic>xylR<\/jats:italic>\n            (\n            <jats:italic>mecR2<\/jats:italic>\n            ), and PSM-\n            <jats:italic>mec<\/jats:italic>\n            (phenol-soluble modulin) were absent. We suggest that\n            <jats:italic>mec<\/jats:italic>\n            complex A should be split into two subtypes. One harbors PSM-\n            <jats:italic>mec<\/jats:italic>\n            and\n            <jats:italic>xylR<\/jats:italic>\n            (\n            <jats:italic>mecR2<\/jats:italic>\n            ). It is found in SCC\n            <jats:italic>mec<\/jats:italic>\n            types II, III, and VIII. The second subtype, described herein, is present in WA MRSA-59 and some coagulase-negative staphylococci.\n          <\/jats:p>","DOI":"10.1128\/aac.01745-15","type":"journal-article","created":{"date-parts":[[2015,9,9]],"date-time":"2015-09-09T02:21:18Z","timestamp":1441765278000},"page":"7142-7144","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":4,"title":["A Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCC\n            <i>mec<\/i>\n            Element"],"prefix":"10.1128","volume":"59","author":[{"given":"Stefan","family":"Monecke","sequence":"first","affiliation":[{"name":"Alere Technologies GmbH, Jena, Germany"},{"name":"Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technische Universit\u00e4t Dresden, Dresden, Germany"},{"name":"InfectoGnostics, Forschungscampus, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geoffrey W.","family":"Coombs","sequence":"additional","affiliation":[{"name":"Australian Collaborating Centre for Enterococcus and Staphylococcus Species (ACCESS) Typing and Research, Murdoch University, Murdoch, Western Australia, Australia"},{"name":"Department of Microbiology, PathWest Laboratory Medicine WA, Fiona Stanley Hospital, Murdoch, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Pearson","sequence":"additional","affiliation":[{"name":"Department of Microbiology, PathWest Laboratory Medicine WA, Fiona Stanley Hospital, Murdoch, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helmut","family":"Hotzel","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Bacterial Infections and Zoonoses, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Slickers","sequence":"additional","affiliation":[{"name":"Alere Technologies GmbH, Jena, Germany"},{"name":"InfectoGnostics, Forschungscampus, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralf","family":"Ehricht","sequence":"additional","affiliation":[{"name":"Alere Technologies GmbH, Jena, Germany"},{"name":"InfectoGnostics, Forschungscampus, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2014.06.007"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00574-12"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00187-11"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00579-09"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2013.02.002"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2015.01.009"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/518726"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-11-215"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017936"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01745-15","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01745-15","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T22:42:06Z","timestamp":1645483326000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.01745-15"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.1128\/AAC.01745-15"],"URL":"https:\/\/doi.org\/10.1128\/aac.01745-15","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11]]},"assertion":[{"value":"2015-07-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-08-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-10-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}