{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:13:26Z","timestamp":1787314406548,"version":"build-2736575974"},"reference-count":20,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T00:00:00Z","timestamp":1748995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T00:00:00Z","timestamp":1748995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100003042","name":"Else Kroener-Fresenius-Stiftung","doi-asserted-by":"publisher","award":["2022_EKHA.170"],"award-info":[{"award-number":["2022_EKHA.170"]}],"id":[{"id":"10.13039\/501100003042","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2025,6,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      In Fort Portal, Uganda, artemisinin resistance-associated mutations in\n                      <jats:italic toggle=\"yes\">Plasmodium falciparum Kelch13<\/jats:italic>\n                      (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 126) were present in 4.8% (675V, 561H, and 441L). A mutation of unknown relevance, 490T, occurred in 9.5%.\n                      <jats:italic toggle=\"yes\">PfMDR1<\/jats:italic>\n                      variants suggested increased lumefantrine tolerance (N86, 100%). Mutation 500N was absent, and 199S occurred in 12.8%. The latter is of unknown relevance. These data indicate an incipient emergence of artemisinin resistance in a crucial location between Rwandan and Ugandan resistance hotspots and hardly affected DR Congo.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/aac.01755-24","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T09:03:06Z","timestamp":1745398986000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":2,"title":["<i>Plasmodium falciparum Kelch-13<\/i>\n                    artemisinin partial resistance markers in Fort Portal, Western Uganda, 2024"],"prefix":"10.1128","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3331-3997","authenticated-orcid":true,"given":"Welmoed","family":"van Loon","sequence":"first","affiliation":[{"name":"Institute of International Health, Charit\u00e9 Center for Global Health, Charit\u00e9-Universitaetsmedizin Berlin","place":["Berlin, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Schallenberg","sequence":"additional","affiliation":[{"name":"Institute of International Health, Charit\u00e9 Center for Global Health, Charit\u00e9-Universitaetsmedizin Berlin","place":["Berlin, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Mande","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02caa0269","id-type":"ROR","asserted-by":"publisher"}],"name":"Infectious Diseases Institute, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Musinguzi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02rpzg225","id-type":"ROR","asserted-by":"publisher"}],"name":"Fort Portal Regional Referral Hospital","place":["Fort Portal, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Ngobi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02rpzg225","id-type":"ROR","asserted-by":"publisher"}],"name":"Fort Portal Regional Referral Hospital","place":["Fort Portal, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Atukunda","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02rpzg225","id-type":"ROR","asserted-by":"publisher"}],"name":"Fort Portal Regional Referral Hospital","place":["Fort Portal, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Rubaihayo","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03s5r1026","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Public Health, Mountains of the Moon University","place":["Fort Portal, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank P.","family":"Mockenhaupt","sequence":"additional","affiliation":[{"name":"Institute of International Health, Charit\u00e9 Center for Global Health, Charit\u00e9-Universitaetsmedizin Berlin","place":["Berlin, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","unstructured":"World Health O. 2023. 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