{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T23:35:27Z","timestamp":1772148927533,"version":"3.50.1"},"reference-count":10,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2011,5]]},"abstract":"ABSTRACT<\/jats:title>\n \n A 72-year-old man, receiving 8 mg daptomycin\/kg body weight\/day for methicillin-resistant\n Staphylococcus aureus<\/jats:named-content>\n (MRSA) bacteremia, was diagnosed with MRSA\/vancomycin-resistant\n Enterococcus faecium<\/jats:named-content>\n (VRE) cholecystitis (daptomycin MIC values, 1 and 2 mg\/liter, respectively). After the fifth drug dose, the bile concentration of daptomycin was 66 mg\/liter 5 min after drug administration, with the biliary concentration\/MIC values higher than 30 for both bacterial strains. Therefore, daptomycin achieved therapeutic levels in bile, hence suggesting a role for the drug in the treatment of MRSA\/VRE cholecystitis.\n <\/jats:p>","DOI":"10.1128\/aac.01774-10","type":"journal-article","created":{"date-parts":[[2011,2,23]],"date-time":"2011-02-23T04:16:50Z","timestamp":1298434610000},"page":"2458-2459","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":26,"title":["Case Report of a Successful Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Bacteremia and MRSA\/Vancomycin-Resistant Enterococcus faecium Cholecystitis by Daptomycin"],"prefix":"10.1128","volume":"55","author":[{"given":"Carlo","family":"Tascini","sequence":"first","affiliation":[{"name":"Infectious Diseases Unit, Santa Chiara University Hospital, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonello","family":"Di Paolo","sequence":"additional","affiliation":[{"name":"Division of Pharmacology, Department of Internal Medicine, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marialuisa","family":"Polillo","sequence":"additional","affiliation":[{"name":"Division of Pharmacology, Department of Internal Medicine, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of Oncology, Transplants and New Technologies in Medicine, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Lambelet","sequence":"additional","affiliation":[{"name":"Division of Medicine, Versilia Hospital, Camaiore, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romano","family":"Danesi","sequence":"additional","affiliation":[{"name":"Division of Pharmacology, Department of Internal Medicine, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Menichetti","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, Santa Chiara University Hospital, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00247-06"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00943-08"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2005.01138.x"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1358\/dot.2009.45.1.1315922"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2008.12.007"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e3181d3f5cb"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1P307"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.1.63-68.2004"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1592\/phco.30.12.1247"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq109"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01774-10","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.01774-10","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T23:27:49Z","timestamp":1645486069000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.01774-10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["10.1128\/AAC.01774-10"],"URL":"https:\/\/doi.org\/10.1128\/aac.01774-10","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5]]},"assertion":[{"value":"2010-12-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-02-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-04-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}