{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:10:52Z","timestamp":1791292252039,"version":"4.1.0"},"reference-count":39,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Acinetobacter baumannii<\/jats:named-content>\n            isolate AP2 was recovered from a bronchial lavage sample of a patient hospitalized in Paris, France.\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">A. baumannii<\/jats:named-content>\n            AP2 was resistant to all \u03b2-lactams, including carbapenems, and expressed the extended-spectrum \u03b2-lactamase (ESBL) PER-7, which differs from PER-1 by 4 amino acid substitutions. Compared to PER-1, PER-7 possessed higher-level hydrolytic activities against cephalosporins and aztreonam. The\n            <jats:italic>bla<\/jats:italic>\n            <jats:sub>PER-7<\/jats:sub>\n            gene was chromosomally located and associated with a mosaic class 1 integron structure. Additionally, isolate AP2 expressed the carbapenem-hydrolyzing oxacillinase OXA-23 and the 16S RNA methylase ArmA, conferring high-level resistance to aminoglycosides.\n          <\/jats:p>","DOI":"10.1128\/aac.01795-10","type":"journal-article","created":{"date-parts":[[2011,3,8]],"date-time":"2011-03-08T07:04:54Z","timestamp":1299567894000},"page":"2424-2427","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":59,"title":["PER-7, an Extended-Spectrum \u03b2-Lactamase with Increased Activity toward Broad-Spectrum Cephalosporins in Acinetobacter baumannii"],"prefix":"10.1128","volume":"55","author":[{"given":"R\u00e9my A.","family":"Bonnin","sequence":"first","affiliation":[{"name":"Service de Bact\u00e9riologie-Virologie, INSERM U914 \u201cEmerging Resistance to Antibiotics,\u201d H\u00f4pital de Bic\u00eatre, Assistance Publique\/H\u00f4pitaux de Paris, Facult\u00e9 de M\u00e9decine et Universit\u00e9 Paris-Sud, Le Kremlin-Bic\u00eatre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana\u00efs","family":"Potron","sequence":"additional","affiliation":[{"name":"Service de Bact\u00e9riologie-Virologie, INSERM U914 \u201cEmerging Resistance to Antibiotics,\u201d H\u00f4pital de Bic\u00eatre, Assistance Publique\/H\u00f4pitaux de Paris, Facult\u00e9 de M\u00e9decine et Universit\u00e9 Paris-Sud, Le Kremlin-Bic\u00eatre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Poirel","sequence":"additional","affiliation":[{"name":"Service de Bact\u00e9riologie-Virologie, INSERM U914 \u201cEmerging Resistance to Antibiotics,\u201d H\u00f4pital de Bic\u00eatre, Assistance Publique\/H\u00f4pitaux de Paris, Facult\u00e9 de M\u00e9decine et Universit\u00e9 Paris-Sud, Le Kremlin-Bic\u00eatre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herv\u00e9","family":"Lecuyer","sequence":"additional","affiliation":[{"name":"Laboratoire de Microbiologie Hygi\u00e8ne Hospitali\u00e8re, H\u00f4pital Necker-Enfants Malades Assistance Publique-H\u00f4pitaux de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Neri","sequence":"additional","affiliation":[{"name":"Service de Bact\u00e9riologie-Virologie, INSERM U914 \u201cEmerging Resistance to Antibiotics,\u201d H\u00f4pital de Bic\u00eatre, Assistance Publique\/H\u00f4pitaux de Paris, Facult\u00e9 de M\u00e9decine et Universit\u00e9 Paris-Sud, Le Kremlin-Bic\u00eatre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrice","family":"Nordmann","sequence":"additional","affiliation":[{"name":"Service de Bact\u00e9riologie-Virologie, INSERM U914 \u201cEmerging Resistance to Antibiotics,\u201d H\u00f4pital de Bic\u00eatre, Assistance Publique\/H\u00f4pitaux de Paris, Facult\u00e9 de M\u00e9decine et Universit\u00e9 Paris-Sud, Le Kremlin-Bic\u00eatre"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj2760269"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.9.2.148"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00773-10"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/504477"},{"key":"e_1_3_2_6_2","volume-title":"CLSI M100-S20","author":"Clinical and Laboratory Standards Institute.","year":"2010","unstructured":"Clinical and Laboratory Standards Institute. 2010. 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