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We aim to determine the short-term benefits of appropriate empirical antimicrobial treatment (AEAT) with ceftolozane\/tazobactam (C\/T) compared with IEAT with piperacillin\/tazobactam (TZP) in MDR\n            <jats:named-content content-type=\"genus-species\">Pseudomonas aeruginosa<\/jats:named-content>\n            pneumonia. Twenty-one pigs with pneumonia caused by an XDR\n            <jats:named-content content-type=\"genus-species\">P. aeruginosa<\/jats:named-content>\n            strain (susceptible to C\/T but resistant to TZP) were ventilated for up to 72 h.\n          <\/jats:p>","DOI":"10.1128\/aac.01899-20","type":"journal-article","created":{"date-parts":[[2020,11,4]],"date-time":"2020-11-04T14:21:11Z","timestamp":1604499671000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":5,"title":["Short-Term Effects of Appropriate Empirical Antimicrobial Treatment with Ceftolozane\/Tazobactam in a Swine Model of Nosocomial Pneumonia"],"prefix":"10.1128","volume":"65","author":[{"given":"Ana","family":"Motos","sequence":"first","affiliation":[{"name":"Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Cl\u00ednic, Barcelona, Spain"},{"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"},{"name":"Centro de Investigaci\u00f3n Biomedica En Red-Enfermedades Respiratorias (CIBERES), Barcelona, Spain"},{"name":"University of Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluigi","family":"Li Bassi","sequence":"additional","affiliation":[{"name":"Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Cl\u00ednic, Barcelona, Spain"},{"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"},{"name":"Centro de Investigaci\u00f3n Biomedica En Red-Enfermedades Respiratorias (CIBERES), Barcelona, Spain"},{"name":"Critical Care Research Group, The Prince Charles Hospital, Chermside, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Pagliara","sequence":"additional","affiliation":[{"name":"Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Cl\u00ednic, Barcelona, Spain"},{"name":"Department of Surgical Sciences and Integrated Diagnostics (DISC), IRCCS AOU San Martino IST, Genoa, Italy"},{"name":"San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laia","family":"Fernandez-Barat","sequence":"additional","affiliation":[{"name":"Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Cl\u00ednic, Barcelona, Spain"},{"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"},{"name":"Centro de Investigaci\u00f3n Biomedica En Red-Enfermedades Respiratorias (CIBERES), Barcelona, Spain"},{"name":"University of Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Cl\u00ednic, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eli","family":"Aguilera Xiol","sequence":"additional","affiliation":[{"name":"Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Cl\u00ednic, Barcelona, Spain"},{"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"},{"name":"Centro de Investigaci\u00f3n Biomedica En Red-Enfermedades Respiratorias (CIBERES), Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarek","family":"Senussi","sequence":"additional","affiliation":[{"name":"Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Cl\u00ednic, Barcelona, Spain"},{"name":"Department of Surgical Sciences and Integrated Diagnostics (DISC), IRCCS AOU San Martino IST, Genoa, Italy"},{"name":"San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco A.","family":"Idone","sequence":"additional","affiliation":[{"name":"Division of Animal Experimentation, Department of Pulmonary and Critical Care Medicine, Hospital Cl\u00ednic, Barcelona, Spain"},{"name":"Department of Anesthesiology, Intensive Care, and Emergency Medicine, Fondazione Policlinico Universitario A. 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