{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T03:03:42Z","timestamp":1792292622214,"version":"4.4.0"},"reference-count":34,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T00:00:00Z","timestamp":1582243200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T00:00:00Z","timestamp":1582243200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81601797"],"award-info":[{"award-number":["81601797"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81902033"],"award-info":[{"award-number":["81902033"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2020,2,21]]},"abstract":"<jats:p>\n            This study aimed to evaluate the\n            <jats:italic>in vitro<\/jats:italic>\n            antimicrobial activity, heteroresistance emergence, and resistance mechanism of omadacycline (OMC) in clinical\n            <jats:named-content content-type=\"genus-species\">Enterococcus faecalis<\/jats:named-content>\n            isolates from China. A total of 276 isolates were collected retrospectively in China from 2011 to 2015. The MICs of OMC, doxycycline (DOX), and minocycline (MIN) against\n            <jats:named-content content-type=\"genus-species\">E. faecalis<\/jats:named-content>\n            were determined by broth microdilution. Tetracycline (TET)-specific resistance genes and multilocus sequence typing (MLST) of the isolates were investigated using PCR.\n          <\/jats:p>","DOI":"10.1128\/aac.02097-19","type":"journal-article","created":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T13:26:06Z","timestamp":1577107566000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":22,"title":["Omadacycline Efficacy against Enterococcus faecalis Isolated in China:\n            <i>In Vitro<\/i>\n            Activity, Heteroresistance, and Resistance Mechanisms"],"prefix":"10.1128","volume":"64","author":[{"given":"Zhiwei","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases and Shenzhen Key Laboratory for Endogenous Infections, Affiliated Shenzhen Sixth Hospital of Guangdong Medical University, Shenzhen, China"},{"name":"Quality Control Center of Hospital Infection Management of Shenzhen, Shenzhen Nanshan 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