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Policy makers in Cambodia have been reluctant to implement this recommendation due to primaquine safety concerns and a lack of data on its efficacy.\n          <\/jats:p>","DOI":"10.1128\/aac.02108-19","type":"journal-article","created":{"date-parts":[[2020,3,13]],"date-time":"2020-03-13T12:28:36Z","timestamp":1584102516000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":10,"title":["Significant Efficacy of a Single Low Dose of Primaquine Compared to Stand-Alone Artemisinin Combination Therapy in Reducing Gametocyte Carriage in Cambodian Patients with Uncomplicated Multidrug-Resistant Plasmodium falciparum Malaria"],"prefix":"10.1128","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7945-961X","authenticated-orcid":false,"given":"Am\u00e9lie","family":"Vantaux","sequence":"first","affiliation":[{"name":"Malaria Molecular Epidemiology Unit, Institut Pasteur of Cambodia, Phnom Penh, Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saorin","family":"Kim","sequence":"additional","affiliation":[{"name":"Malaria Molecular Epidemiology Unit, Institut Pasteur of Cambodia, Phnom Penh, Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eakpor","family":"Piv","sequence":"additional","affiliation":[{"name":"Malaria Molecular Epidemiology Unit, Institut Pasteur of Cambodia, Phnom Penh, Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophy","family":"Chy","sequence":"additional","affiliation":[{"name":"Malaria Molecular Epidemiology Unit, Institut Pasteur of Cambodia, Phnom Penh, Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Berne","sequence":"additional","affiliation":[{"name":"Malaria Molecular Epidemiology Unit, Institut Pasteur of Cambodia, Phnom Penh, Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimol","family":"Khim","sequence":"additional","affiliation":[{"name":"Malaria Molecular Epidemiology Unit, Institut Pasteur of Cambodia, Phnom Penh, Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dysoley","family":"Lek","sequence":"additional","affiliation":[{"name":"National Center for Parasitology, Entomology and Malaria Control Program, Phnom Penh, Cambodia"},{"name":"School of Public Health, National Institute of Public Health, Phnom Penh, Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sovannaroth","family":"Siv","sequence":"additional","affiliation":[{"name":"National Center for Parasitology, Entomology and Malaria Control Program, Phnom Penh, Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mavuto","family":"Mukaka","sequence":"additional","affiliation":[{"name":"Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand"},{"name":"Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter R.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand"},{"name":"Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"M\u00e9nard","sequence":"additional","affiliation":[{"name":"Malaria Molecular Epidemiology Unit, Institut Pasteur of Cambodia, Phnom Penh, Cambodia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.30875\/7e6f8c91-en"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0805011"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0808859"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1403007"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00835-15"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30524-8"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(19)30391-3"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(03)15162-8"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007483.pub2:CD007483"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm3005898"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1086\/319689"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3156.2003.01169.x"},{"key":"e_1_3_2_14_2","volume-title":"Single dose primaquine as gametocytocide in Plasmodium falciparum malaria","author":"World Health Organization","year":"2012","unstructured":"World Health Organization. 2012. 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