{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T08:12:37Z","timestamp":1789719157111,"version":"4.0.1"},"reference-count":32,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T00:00:00Z","timestamp":1585008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2020,3,24]]},"abstract":"<jats:p>\n            <jats:named-content content-type=\"genus-species\">Klebsiella pneumoniae<\/jats:named-content>\n            carbapenemase-producing\n            <jats:named-content content-type=\"genus-species\">Klebsiella pneumoniae<\/jats:named-content>\n            (KPC-\n            <jats:italic>Kp<\/jats:italic>\n            ) is an emerging global public health threat that causes life-threatening pneumonia and bacteremia. Ceftazidime-avibactam (CZA) represents a promising advance for the treatment of serious infections caused by KPC-\n            <jats:italic>Kp<\/jats:italic>\n            . We investigated the pharmacokinetics and efficacy of ceftazidime-avibactam in the treatment of experimental KPC-\n            <jats:italic>Kp<\/jats:italic>\n            pneumonia in persistently neutropenic rabbits.\n          <\/jats:p>","DOI":"10.1128\/aac.02157-19","type":"journal-article","created":{"date-parts":[[2020,1,31]],"date-time":"2020-01-31T10:02:22Z","timestamp":1580464942000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":11,"title":["Pharmacokinetics and Efficacy of Ceftazidime-Avibactam in the Treatment of Experimental Pneumonia Caused by Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae in Persistently Neutropenic Rabbits"],"prefix":"10.1128","volume":"64","author":[{"given":"Ruta","family":"Petraitiene","sequence":"first","affiliation":[{"name":"Transplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine of 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