{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T06:43:42Z","timestamp":1775889822106,"version":"3.50.1"},"reference-count":54,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T00:00:00Z","timestamp":1585008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Niedersachsen Vorab","award":["Coalition"],"award-info":[{"award-number":["Coalition"]}]},{"DOI":"10.13039\/100009139","name":"Deutsches Zentrum f\u00fcr Infektionsforschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009139","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2020,3,24]]},"abstract":"<jats:p>\n            Infections with enterohemorrhagic\n            <jats:named-content content-type=\"genus-species\">Escherichia coli<\/jats:named-content>\n            (EHEC) cause disease ranging from mild diarrhea to hemolytic-uremic syndrome (HUS) and are the most common cause of renal failure in children in high-income countries. The severity of the disease derives from the release of Shiga toxins (Stx). The use of antibiotics to treat EHEC infections is generally avoided, as it can result in increased\n            <jats:italic>stx<\/jats:italic>\n            expression. Here, we systematically tested different classes of antibiotics and found that their influence on\n            <jats:italic>stx<\/jats:italic>\n            expression and release varies significantly.\n          <\/jats:p>","DOI":"10.1128\/aac.02159-19","type":"journal-article","created":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T10:39:06Z","timestamp":1580812746000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":25,"title":["Identification of Antibiotics That Diminish Disease in a Murine Model of Enterohemorrhagic Escherichia coli Infection"],"prefix":"10.1128","volume":"64","author":[{"given":"Sabrina","family":"M\u00fchlen","sequence":"first","affiliation":[{"name":"Department of Molecular Infection Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany"},{"name":"Institute for Infectiology, University of M\u00fcnster, M\u00fcnster, Germany"},{"name":"German Center for Infection Research 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