{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:20:45Z","timestamp":1790882445740,"version":"4.1.0"},"reference-count":22,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Scientific Research Foundation of Sichuan University","award":["2017SCU12006"],"award-info":[{"award-number":["2017SCU12006"]}]},{"name":"Special Fund for Agro-Scientific Research in the Public Interest of China","award":["201303044"],"award-info":[{"award-number":["201303044"]}]},{"DOI":"10.13039\/501100009997","name":"Earmarked Fund for Modern Agro-Industry Technology Research System","doi-asserted-by":"crossref","award":["CARS-40-K14"],"award-info":[{"award-number":["CARS-40-K14"]}],"id":[{"id":"10.13039\/501100009997","id-type":"DOI","asserted-by":"crossref"}]},{"name":"General Program of National Natural Science Foundation of China","award":["31572547"],"award-info":[{"award-number":["31572547"]}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A novel 65.8-kb multidrug resistance transposon, designated Tn\n            <jats:italic>6450<\/jats:italic>\n            , was characterized in a\n            <jats:named-content content-type=\"genus-species\">Proteus mirabilis<\/jats:named-content>\n            isolate from chicken in China. Tn\n            <jats:italic>6450<\/jats:italic>\n            contains 18 different antimicrobial resistance genes, including cephalosporinase gene\n            <jats:italic>bla<\/jats:italic>\n            <jats:sub>DHA-1<\/jats:sub>\n            and fluoroquinolone resistance genes\n            <jats:italic>qnrA1<\/jats:italic>\n            and\n            <jats:italic>aac(6<\/jats:italic>\n            \u2032\n            <jats:italic>)-Ib-cr<\/jats:italic>\n            . It carries a class 1\/2 hybrid integron composed of\n            <jats:italic>intI2<\/jats:italic>\n            and a 3\u2032 conserved segment of the class 1 integron. Tn\n            <jats:italic>6450<\/jats:italic>\n            is derived from Tn\n            <jats:italic>7<\/jats:italic>\n            via acquisition of new mobile elements and resistance genes.\n          <\/jats:p>","DOI":"10.1128\/aac.02192-17","type":"journal-article","created":{"date-parts":[[2018,1,18]],"date-time":"2018-01-18T11:31:20Z","timestamp":1516275080000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":23,"title":["Tn\n            <i>6450<\/i>\n            , a Novel Multidrug Resistance Transposon Characterized in a Proteus mirabilis Isolate from Chicken in China"],"prefix":"10.1128","volume":"62","author":[{"given":"Yan-Peng","family":"Chen","sequence":"first","affiliation":[{"name":"Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Wei","family":"Lei","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling-Han","family":"Kong","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Xin","family":"Zeng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life 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