{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T10:44:34Z","timestamp":1780397074204,"version":"3.54.1"},"reference-count":13,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T00:00:00Z","timestamp":1655769600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T00:00:00Z","timestamp":1655769600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2022,6,21]]},"abstract":"<jats:p>\n            Antifungal drug susceptibility tests (AST) for\n            <jats:named-content content-type=\"genus-species\">Candida albicans<\/jats:named-content>\n            are increasingly demanded for women with refractory or recurrent\n            <jats:italic>Candida<\/jats:italic>\n            vaginitis due to fluconazole resistance. Given reduced activity of azole drugs at pH levels found in women with\n            <jats:italic>Candida<\/jats:italic>\n            vaginitis, it is proposed that AST be performed at pH 4.5, since testing at only the recommended pH 7.0 is likely to miss a significant number of clinically relevant azole-resistant\n            <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n            vaginal isolates.\n          <\/jats:p>","DOI":"10.1128\/aac.02366-21","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T13:03:55Z","timestamp":1653311035000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":16,"title":["Determining Susceptibility in\n            <i>Candida<\/i>\n            Vaginal Isolates"],"prefix":"10.1128","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5589-4609","authenticated-orcid":true,"given":"Jack D.","family":"Sobel","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Wayne State University, Detroit, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Akins","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Microbiology, and Immunology, Wayne State University, Detroit, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31827307b2"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0000000000000383"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2011.03.016"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5598907"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.riam.2021.03.002"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0000000000000496"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.06.067"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S179462"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.06.007"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofab444"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00069-19"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05025-11"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.43.6.1383"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aac.02366-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aac.02366-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T14:50:35Z","timestamp":1655823035000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/aac.02366-21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,21]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6,21]]}},"alternative-id":["10.1128\/aac.02366-21"],"URL":"https:\/\/doi.org\/10.1128\/aac.02366-21","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,21]]},"assertion":[{"value":"2021-12-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e02366-21"}}