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Recently, several derivatives of endochin have been optimized to produce novel quinolones that are active\n            <jats:italic>in vitro<\/jats:italic>\n            and in animal models. While these quinolones exhibit potent\n            <jats:italic>ex vivo<\/jats:italic>\n            activity against\n            <jats:named-content content-type=\"genus-species\">Plasmodium falciparum<\/jats:named-content>\n            and\n            <jats:named-content content-type=\"genus-species\">Plasmodium vivax<\/jats:named-content>\n            , their activity against the zoonotic agent\n            <jats:named-content content-type=\"genus-species\">Plasmodium knowlesi<\/jats:named-content>\n            is unknown.\n          <\/jats:p>","DOI":"10.1128\/aac.02549-19","type":"journal-article","created":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T15:52:10Z","timestamp":1583941930000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":19,"title":["Novel Endochin-Like Quinolones Exhibit Potent\n            <i>In Vitro<\/i>\n            Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil"],"prefix":"10.1128","volume":"64","author":[{"given":"Donelly A.","family":"van Schalkwyk","sequence":"first","affiliation":[{"name":"Department of Infection Biology, Faculty of Infectious &amp; Tropical Diseases, London School of Hygiene &amp; Tropical Medicine, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael K.","family":"Riscoe","sequence":"additional","affiliation":[{"name":"Veterans Affairs Medical Center, Portland, Oregon, USA"},{"name":"Department of Molecular Microbiology and Immunology, Oregon Health &amp; Science University, Portland, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sovitj","family":"Pou","sequence":"additional","affiliation":[{"name":"Veterans Affairs Medical Center, Portland, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf W.","family":"Winter","sequence":"additional","affiliation":[{"name":"Veterans Affairs Medical Center, Portland, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Nilsen","sequence":"additional","affiliation":[{"name":"Veterans Affairs Medical Center, Portland, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u00eblle","family":"Duffey","sequence":"additional","affiliation":[{"name":"Medicines for Malaria Venture, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert W.","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Infection Biology, Faculty of Infectious &amp; Tropical Diseases, London School of Hygiene &amp; Tropical Medicine, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1592-6407","authenticated-orcid":false,"given":"Colin J.","family":"Sutherland","sequence":"additional","affiliation":[{"name":"Department of Infection Biology, Faculty of Infectious &amp; Tropical Diseases, London School of Hygiene &amp; Tropical Medicine, London, United Kingdom"},{"name":"Department of Clinical Parasitology, Hospital for Tropical Diseases, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","unstructured":"World Health Organization. 2019. 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