{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T21:38:21Z","timestamp":1771364301138,"version":"3.50.1"},"reference-count":9,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Paratek Pharmaceuticals Inc."}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Omadacycline was tested against 125 isolates recovered from infected cat and dog bites in humans. Its activity was similar to that of other compounds in the tetracycline class, and it was active against strains exhibiting tetracycline resistance. Against anaerobic isolates, resistance to tetracyclines was more prominent and omadacycline was the most active of the group. All isolates had omadacycline MICs of &lt;1 \u03bcg\/ml, with the exception of\n            <jats:named-content content-type=\"genus-species\">Eikenella corrodens<\/jats:named-content>\n            , which showed reduced susceptibility to the entire tetracycline group.\n          <\/jats:p>","DOI":"10.1128\/aac.02551-17","type":"journal-article","created":{"date-parts":[[2018,2,10]],"date-time":"2018-02-10T12:57:19Z","timestamp":1518267439000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":15,"title":["Comparative\n            <i>In Vitro<\/i>\n            Activity of Omadacycline against Dog and Cat Bite Wound Isolates"],"prefix":"10.1128","volume":"62","author":[{"given":"Ellie J. C.","family":"Goldstein","sequence":"first","affiliation":[{"name":"R. M. Alden Research Lab, Culver City, California, USA"},{"name":"David Geffen School of Medicine at UCLA, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane M.","family":"Citron","sequence":"additional","affiliation":[{"name":"R. M. Alden Research Lab, Culver City, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerin L.","family":"Tyrrell","sequence":"additional","affiliation":[{"name":"R. M. Alden Research Lab, Culver City, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliza","family":"Leoncio","sequence":"additional","affiliation":[{"name":"R. M. Alden Research Lab, Culver City, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Vreni","family":"Merriam","sequence":"additional","affiliation":[{"name":"R. M. Alden Research Lab, Culver City, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","volume-title":"Pets by the numbers: U.S. pet ownership, community cat and shelter population estimates","author":"The Humane Society of the United States","year":"2016","unstructured":"The Humane Society of the United States. 2016. Pets by the numbers: U.S. pet ownership, community cat and shelter population estimates. The Humane Society of the United States, Washington, DC. http:\/\/www.humanesociety.org\/issues\/pet_overpopulation\/facts\/pet_ownership_statistics.htm. 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CLSI, Wayne, PA.","edition":"8"},{"key":"e_1_3_2_9_2","volume-title":"CLSI document M45-A3E","author":"Clinical and Laboratory Standards Institute","year":"2015","unstructured":"Clinical and Laboratory Standards Institute. 2015. Methods for antimicrobial dilution and disc susceptibility testing of infrequently isolated or fastidious bacteria, approved standard, 3rd edition. CLSI document M45-A3E. CLSI, Wayne, PA.","edition":"3"},{"key":"e_1_3_2_10_2","volume-title":"CLSI document M100-S27","author":"Clinical and Laboratory Standards Institute","year":"2017","unstructured":"Clinical and Laboratory Standards Institute. 2017. Performance standards for antimicrobial susceptibility testing, 27th informational supplement. CLSI document M100-S27. CLSI, Wayne, PA."}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.02551-17","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.02551-17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T21:13:00Z","timestamp":1645477980000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.02551-17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1128\/AAC.02551-17"],"URL":"https:\/\/doi.org\/10.1128\/aac.02551-17","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"2017-12-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-02-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e02551-17"}}