{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T11:54:46Z","timestamp":1765886086059,"version":"3.41.2"},"reference-count":6,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Humco"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            In an effort to increase the efficacy of topical medications for treating onychomycosis, several new nail penetration enhancers were recently developed. In this study, the ability of 10% (wt\/wt) miconazole nitrate combined with a penetration enhancer formulation to permeate the nail is demonstrated by the use of a selection of\n            <jats:italic>in vitro<\/jats:italic>\n            nail penetration assays. These assays included the bovine hoof, TurChub zone of inhibition, and infected-nail models.\n          <\/jats:p>","DOI":"10.1128\/aac.02554-16","type":"journal-article","created":{"date-parts":[[2017,4,25]],"date-time":"2017-04-25T00:55:26Z","timestamp":1493081726000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of the Ability of a Novel Miconazole Formulation To Penetrate Nail by Using Three\n            <i>In Vitro<\/i>\n            Nail Models"],"prefix":"10.1128","volume":"61","author":[{"given":"Luisa","family":"Christensen","sequence":"first","affiliation":[{"name":"Center for Medical Mycology, Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA"},{"name":"University Hospitals Case Medical Center, Cleveland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rob","family":"Turner","sequence":"additional","affiliation":[{"name":"MedPharm Ltd., Surrey Research Park, Guildford, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean","family":"Weaver","sequence":"additional","affiliation":[{"name":"MedPharm Ltd., Surrey Research Park, Guildford, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Caserta","sequence":"additional","affiliation":[{"name":"MedPharm Ltd., Surrey Research Park, Guildford, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Long","sequence":"additional","affiliation":[{"name":"Center for Medical Mycology, Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA"},{"name":"University Hospitals Case Medical Center, Cleveland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud","family":"Ghannoum","sequence":"additional","affiliation":[{"name":"Center for Medical Mycology, Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA"},{"name":"University Hospitals Case Medical Center, Cleveland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Brown","sequence":"additional","affiliation":[{"name":"MedPharm Ltd., Surrey Research Park, Guildford, United Kingdom"},{"name":"TDDT, School of Health and Life Sciences, University of Hertfordshire, Hatfield, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.2.305"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.7547\/87507315-93-2-136"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1211\/jpp.62.06.0009"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-007-9368-3"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2008.11.009"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04842-14"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.02554-16","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.02554-16","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T21:01:58Z","timestamp":1645477318000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.02554-16"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":6,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1128\/AAC.02554-16"],"URL":"https:\/\/doi.org\/10.1128\/aac.02554-16","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"type":"print","value":"0066-4804"},{"type":"electronic","value":"1098-6596"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"2016-12-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-04-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e02554-16"}}