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On days 3 to 5, the mean (standard deviation) maximum plasma concentration and area under the concentration versus time curve from 0 to 24 h were 0.74 \u03bcg\/ml (0.61 \u03bcg\/ml) and 9.28 \u03bcg \u00b7 h\/ml (6.30 \u03bcg \u00b7 h\/ml), respectively. The exposure and safety in this small cohort of adolescents were comparable to those for adults. (This study has been registered at ClinicalTrials.gov under registration no. NCT01966055.)<\/jats:p>","DOI":"10.1128\/aac.02561-15","type":"journal-article","created":{"date-parts":[[2016,2,17]],"date-time":"2016-02-17T03:49:32Z","timestamp":1455680972000},"page":"2572-2576","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["Solithromycin Pharmacokinetics in Plasma and Dried Blood Spots and Safety in Adolescents"],"prefix":"10.1128","volume":"60","author":[{"given":"Daniel","family":"Gonzalez","sequence":"first","affiliation":[{"name":"Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debra L.","family":"Palazzi","sequence":"additional","affiliation":[{"name":"Infectious Diseases Section, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leena","family":"Bhattacharya-Mithal","sequence":"additional","affiliation":[{"name":"Ann and Robert H. 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