{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:25:34Z","timestamp":1790198734647,"version":"4.1.0"},"reference-count":18,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002717","name":"Minist\u00e8re de l'Enseignement Sup\u00e9rieur et de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002717","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            <jats:italic>aac(6\u2032)-Ib-cr<\/jats:italic>\n            is a plasmid-mediated quinolone resistance gene embedded within a gene cassette, most often within an integron. It confers resistance to quinolones and aminoglycosides. We investigated the role of a 101-bp fragment frequently present upstream of the\n            <jats:italic>aac(6\u2032)-Ib-cr<\/jats:italic>\n            gene cassette and found that it contributes to the expression of\n            <jats:italic>aac(6\u2032)-Ib-cr<\/jats:italic>\n            and provides an alternative start codon, confirming the length of the AAC(6\u2032)-Ib-cr protein to 199 amino acids.\n          <\/jats:p>","DOI":"10.1128\/aac.02704-16","type":"journal-article","created":{"date-parts":[[2017,2,22]],"date-time":"2017-02-22T01:30:22Z","timestamp":1487727022000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":15,"title":["Expression of the\n            <i>aac(6\u2032)-Ib-cr<\/i>\n            Gene in Class 1 Integrons"],"prefix":"10.1128","volume":"61","author":[{"given":"Sophie","family":"Raherison","sequence":"first","affiliation":[{"name":"University of Limoges, UMR_S1092, Limoges, 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