{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T21:09:19Z","timestamp":1790543359816,"version":"4.1.0"},"reference-count":29,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The\n            <jats:italic>in vitro<\/jats:italic>\n            antimalarial activities of artemisone and artemisone entrapped in Pheroid vesicles were compared, as was their ability to induce dormancy in\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Plasmodium falciparum<\/jats:named-content>\n            . There was no increase in the activity of artemisone entrapped in Pheroid vesicles against multidrug-resistant\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">P. falciparum<\/jats:named-content>\n            lines. Artemisone induced the formation of dormant ring stages similar to dihydroartemisinin. Thus, the Pheroid delivery system neither improved the activity of artemisone nor prevented the induction of dormant rings.\n          <\/jats:p>","DOI":"10.1128\/aac.02707-14","type":"journal-article","created":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T07:44:04Z","timestamp":1412667844000},"page":"7579-7582","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":10,"title":["Assessment of the Induction of Dormant Ring Stages in Plasmodium falciparum Parasites by Artemisone and Artemisone Entrapped in Pheroid Vesicles\n            <i>In Vitro<\/i>"],"prefix":"10.1128","volume":"58","author":[{"given":"Lizette","family":"Grobler","sequence":"first","affiliation":[{"name":"DST\/NWU Preclinical Drug Development Platform, Faculty of Health Sciences, North-West University, Potchefstroom, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Chavchich","sequence":"additional","affiliation":[{"name":"Australian Army Malaria Institute, Enoggera, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard K.","family":"Haynes","sequence":"additional","affiliation":[{"name":"Centre of Excellence for Pharmaceutical Sciences, Faculty of Health Sciences, North-West University, Potchefstroom, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Edstein","sequence":"additional","affiliation":[{"name":"Australian Army Malaria Institute, Enoggera, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne F.","family":"Grobler","sequence":"additional","affiliation":[{"name":"DST\/NWU Preclinical Drug Development Platform, Faculty of Health Sciences, North-West University, Potchefstroom, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","volume-title":"World malaria report 2010","author":"WHO","year":"2010","unstructured":"WHO. 2010. 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In Medicine and health in the tropics. Proceedings of the XVI International Congress for Tropical Medicine and Malaria, Marseilles, France."},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00471-09"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1086\/656476"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-10-56"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-12-391"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05540-11"},{"key":"e_1_3_2_14_2","volume-title":"Abstr. 14th Int. Congr. Tropic. Med. Malar","author":"Kyle DE","year":"1996","unstructured":"KyleDEWebsterHK. 1996. Postantibiotic effect of quinine and dihydroartemisinin on Plasmodium falciparum in vitro: implications for a mechanism of recrudescence, abstr 0-22-6. Abstr. 14th Int. Congr. Tropic. Med. 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