{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:32:45Z","timestamp":1787016765387,"version":"build-2736575974"},"reference-count":32,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"973","award":["2013CB127200"],"award-info":[{"award-number":["2013CB127200"]}]},{"DOI":"10.13039\/501100005847","name":"FHB | Health and Medical Research Fund","doi-asserted-by":"publisher","award":["14130402"],"award-info":[{"award-number":["14130402"]}],"id":[{"id":"10.13039\/501100005847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005847","name":"FHB | Health and Medical Research Fund","doi-asserted-by":"publisher","award":["13121412"],"award-info":[{"award-number":["13121412"]}],"id":[{"id":"10.13039\/501100005847","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Resistance to extended-spectrum \u03b2-lactams in\n                    <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Salmonella<\/jats:named-content>\n                    , in particular, in serotypes such as\n                    <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Salmonella enterica<\/jats:named-content>\n                    serovar Enteritidis that are frequently associated with clinical infections, is a serious public health concern. In this study, phenotypic characterization of 433 clinical\n                    <jats:italic>S<\/jats:italic>\n                    . Enteritidis strains obtained from a nationwide collection of the Chinese Center for Disease Control and Prevention during the period from 2005 to 2010 depicted a trend of increasing resistance to ceftriaxone from 2008 onwards. Seventeen (4%) of the strains were found to be resistant to ceftriaxone, 7% were found to be resistant to ciprofloxacin, and 0.7% were found to be resistant to both ciprofloxacin and ceftriaxone. Most of the ceftriaxone-resistant\n                    <jats:italic>S<\/jats:italic>\n                    . Enteritidis strains (15\/17) were genetically unrelated and originated from Henan Province. The complete sequence of an IncI1 plasmid, pSE115, which belonged to a novel sequence type, was obtained. This 87,255-bp IncI1 plasmid was found to harbor a\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>CTX-M-14<\/jats:sub>\n                    gene in a novel multidrug resistance region (MRR) within the\n                    <jats:italic>tra<\/jats:italic>\n                    locus. Although the majority of strains were also found to contain conjugative IncI1 plasmids with a size similar to that of pSE115 (\u223c90 kb) and harbor a variety of\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>CTX-M<\/jats:sub>\n                    group 1 and group 9 elements, the novel MRR site at the\n                    <jats:italic>tra<\/jats:italic>\n                    locus in pSE115 was not detectable in the other IncI1 plasmids. The findings from this study show that cephalosporin resistance in\n                    <jats:italic>S<\/jats:italic>\n                    . Enteritidis strains collected in China was mainly due to the dissemination of IncI1 plasmids carrying\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>CTX-M<\/jats:sub>\n                    , resembling the situation in which IncI1 plasmids serve as major vectors of\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>CTX-M<\/jats:sub>\n                    variants in other members of the\n                    <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Enterobacteriaceae<\/jats:named-content>\n                    .\n                  <\/jats:p>","DOI":"10.1128\/aac.02746-15","type":"journal-article","created":{"date-parts":[[2015,12,8]],"date-time":"2015-12-08T10:05:43Z","timestamp":1449569143000},"page":"982-989","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":36,"title":["IncI1 Plasmids Carrying Various\n                    <i>bla<\/i>\n                    <sub>CTX-M<\/sub>\n                    Genes Contribute to Ceftriaxone Resistance in Salmonella enterica Serovar Enteritidis in China"],"prefix":"10.1128","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5472-8337","authenticated-orcid":false,"given":"Marcus Ho-yin","family":"Wong","sequence":"first","affiliation":[{"name":"State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"},{"name":"Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biao","family":"Kan","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention (ICDC), Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward Wai-chi","family":"Chan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"},{"name":"Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiying","family":"Yan","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention (ICDC), Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"},{"name":"Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2010.0827"},{"key":"e_1_3_2_3_2","unstructured":"Centers for Disease Control and Prevention. 2011. National enteric disease surveillance: Salmonella annual report 2011. 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