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Here, the\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Plasmodium falciparum<\/jats:named-content>\n            [\n            <jats:sup>3<\/jats:sup>\n            H]hypoxanthine uptake assay was adapted for\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">P. knowlesi<\/jats:named-content>\n            and used to determine the sensitivity of this parasite to chloroquine, cycloguanil, and clindamycin. The data demonstrate that\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">P. knowlesi<\/jats:named-content>\n            is sensitive to all drugs, with 50% inhibitory concentrations (IC\n            <jats:sub>50<\/jats:sub>\n            s) consistent with those obtained with\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">P. falciparum<\/jats:named-content>\n            . This assay provides a platform to use\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">P. knowlesi in vitro<\/jats:named-content>\n            for drug discovery.\n          <\/jats:p>","DOI":"10.1128\/aac.02948-15","type":"journal-article","created":{"date-parts":[[2016,4,26]],"date-time":"2016-04-26T04:08:19Z","timestamp":1461643699000},"page":"4361-4363","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":16,"title":["Adaptation of the [\n            <sup>3<\/sup>\n            H]Hypoxanthine Uptake Assay for\n            <i>In Vitro<\/i>\n            -Cultured Plasmodium knowlesi Malaria Parasites"],"prefix":"10.1128","volume":"60","author":[{"given":"Megan S. J.","family":"Arnold","sequence":"first","affiliation":[{"name":"Eskitis Institute for Drug Discovery, Griffith University, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica A.","family":"Engel","sequence":"additional","affiliation":[{"name":"Eskitis Institute for Drug Discovery, Griffith University, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming Jang","family":"Chua","sequence":"additional","affiliation":[{"name":"Eskitis Institute for Drug Discovery, Griffith University, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian M.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Eskitis Institute for Drug Discovery, Griffith University, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina S.","family":"Skinner-Adams","sequence":"additional","affiliation":[{"name":"Eskitis Institute for Drug Discovery, Griffith University, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine T.","family":"Andrews","sequence":"additional","affiliation":[{"name":"Eskitis Institute for Drug Discovery, Griffith University, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","unstructured":"World Health Organization. 2015. 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Measurement of the lactate dehydrogenase activity of Plasmodium falciparum as an assessment of parasitemia. 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