{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:04:11Z","timestamp":1777579451530,"version":"3.51.4"},"reference-count":29,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The resistance of multidrug-resistant\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Acinetobacter baumannii<\/jats:named-content>\n            (MDRAB) isolates to most traditional antibiotics results in huge challenges for infection therapy. We investigated the\n            <jats:italic>in vitro<\/jats:italic>\n            activities of both\n            <jats:sc>l<\/jats:sc>\n            - and\n            <jats:sc>d<\/jats:sc>\n            -lycosin-I against MDRAB. These two compounds displayed high antibacterial activities and rapid bactericidal effects against MDRAB. Moreover, the compounds retained their activity even at high salt (Mg\n            <jats:sup>2+<\/jats:sup>\n            or Ca\n            <jats:sup>2+<\/jats:sup>\n            ) concentrations. These results demonstrate the potential of lycosin-I to be developed as a new antibiotic.\n          <\/jats:p>","DOI":"10.1128\/aac.03279-14","type":"journal-article","created":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T03:22:56Z","timestamp":1410232976000},"page":"6999-7002","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":28,"title":["<i>In Vitro<\/i>\n            Potential of Lycosin-I as an Alternative Antimicrobial Drug for Treatment of Multidrug-Resistant Acinetobacter baumannii Infections"],"prefix":"10.1128","volume":"58","author":[{"given":"Ling","family":"Wang","sequence":"first","affiliation":[{"name":"The Second Xiangya Hospital of Central South University, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong-Jun","family":"Wang","sequence":"additional","affiliation":[{"name":"The Second Xiangya Hospital of Central South University, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yin-Yin","family":"Liu","sequence":"additional","affiliation":[{"name":"The Second Xiangya Hospital of Central South University, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Li","sequence":"additional","affiliation":[{"name":"The Second Xiangya Hospital of Central South University, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling-Xia","family":"Guo","sequence":"additional","affiliation":[{"name":"The Second Xiangya Hospital of Central South University, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhong-Hua","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Hunan Normal University, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Liu","family":"Shi","sequence":"additional","affiliation":[{"name":"The Second Xiangya Hospital of Central South University, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Hu","sequence":"additional","affiliation":[{"name":"The Second Xiangya Hospital of Central South University, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31829136c3"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00963-13"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000125"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2011.04.326"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2014.18"},{"key":"e_1_3_3_7_2","doi-asserted-by":"crossref","first-page":"266","DOI":"10.17305\/bjbms.2013.2338","article-title":"Investigation of in-vitro susceptibility of multidrug-resistant Acinetobacter baumannii strains isolated from clinical specimens to tigecycline","volume":"13","author":"Tas T","year":"2013","unstructured":"TasTKocogluEMengelogluZBucakOKarab\u00f6rkS. 2013. Investigation of in-vitro susceptibility of multidrug-resistant Acinetobacter baumannii strains isolated from clinical specimens to tigecycline. Bosn. J. Basic Med. Sci. 13:266\u2013270.","journal-title":"Bosn. J. Basic Med. Sci."},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01624-13"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt197"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn249"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2009.02.009"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1476-0711-12-15"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2014.01.026"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(01)00092-5"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/675391"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002030050418"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-2736(99)00197-2"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2005.10.017"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00232-011-9343-0"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.2174\/156652412803833643"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.2174\/15665240113139990045"},{"key":"e_1_3_3_22_2","volume-title":"CLSI document M100-S24","author":"Clinical and Laboratory Standards Institute","year":"2014","unstructured":"Clinical and Laboratory Standards Institute. 2014. Performance standards for antimicrobial susceptibility testing; 24th informational supplement. CLSI document M100-S24. CLSI, Wayne, PA."},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.11.4086-4095.2000"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2011.01.016"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0080-6234201400002000011"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2013.12.002"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.4161\/psb.6.9.16319"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.3.689-694.2002"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.3390\/ph6081055"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M208429200"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.03279-14","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.03279-14","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T22:48:42Z","timestamp":1645483722000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.03279-14"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":29,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1128\/AAC.03279-14"],"URL":"https:\/\/doi.org\/10.1128\/aac.03279-14","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"2014-05-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-09-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-10-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}