{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:17:53Z","timestamp":1761059873052},"reference-count":5,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>Eravacycline is a fluorocycline antibiotic in phase 3 clinical development for complicated intra-abdominal and urinary tract infections. To support its clinical development, a study was conducted to evaluate the effects of various susceptibility test parameters on the MIC values for aerobic bacteria. The results showed that eravacycline appears to be largely unaffected by medium age, medium additives, and other nonstandard assay conditions.<\/jats:p>","DOI":"10.1128\/aac.04727-14","type":"journal-article","created":{"date-parts":[[2015,1,21]],"date-time":"2015-01-21T03:47:42Z","timestamp":1421812062000},"page":"2426-2427","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":3,"title":["<i>In Vitro<\/i>\n            Susceptibility Testing of Eravacycline Is Unaffected by Medium Age and Nonstandard Assay Parameters"],"prefix":"10.1128","volume":"59","author":[{"given":"Trudy H.","family":"Grossman","sequence":"first","affiliation":[{"name":"Tetraphase Pharmaceuticals, Watertown, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris M.","family":"Pillar","sequence":"additional","affiliation":[{"name":"Eurofins Medinet, Chantilly, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel F.","family":"Sahm","sequence":"additional","affiliation":[{"name":"Eurofins Medinet, Chantilly, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joyce A.","family":"Sutcliffe","sequence":"additional","affiliation":[{"name":"Tetraphase Pharmaceuticals, Watertown, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm201465w"},{"key":"e_1_3_1_3_2","volume-title":"Methods for dilution antimicrobial susceptibility for bacteria that grow aerobically; approved standard","author":"Clinical Laboratory Standards Institute","year":"2012","unstructured":"Clinical Laboratory Standards Institute. 2012. Methods for dilution antimicrobial susceptibility for bacteria that grow aerobically; approved standard, 9th ed. CLSI document M07-A9E, vol 32, no. 2. Clinical Laboratory Standards Institute, Wayne, PA.","edition":"9"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.9.3910-3918.2005"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.9.3903-3909.2005"},{"key":"e_1_3_1_6_2","volume-title":"Performance standards for antimicrobial susceptibility testing; 24th informational supplement","author":"Clinical Laboratory Standards Institute","year":"2014","unstructured":"Clinical Laboratory Standards Institute. 2014. Performance standards for antimicrobial susceptibility testing; 24th informational supplement. CLSI document M100-S24, vol. 34, no. 1. 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