{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:29:11Z","timestamp":1791232151642,"version":"4.1.0"},"reference-count":30,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Occidiofungin is a cyclic glyco-lipopeptide produced by\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Burkholderia contaminans<\/jats:named-content>\n            . MICs against\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Candida<\/jats:named-content>\n            species were between 0.5 and 2.0 \u03bcg\/ml. Occidiofungin retains its\n            <jats:italic>in vitro<\/jats:italic>\n            potency in the presence of 5% and 50% human serum with a minimal lethal concentration (MLC) of 2 and 4 \u03bcg\/ml, respectively. Time-kill and postantifungal effect (PAFE) experiments of occidiofungin against\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Candida albicans<\/jats:named-content>\n            were performed. The results demonstrate that occidiofungin is fungicidal. Occidiofungin was also found to be a very stable molecule. It is resistant to extreme temperatures and pH and maintains its activity following exposure to gastric proteases.\n          <\/jats:p>","DOI":"10.1128\/aac.05231-11","type":"journal-article","created":{"date-parts":[[2011,11,22]],"date-time":"2011-11-22T07:21:24Z","timestamp":1321946484000},"page":"765-769","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":38,"title":["Occidiofungin's Chemical Stability and\n            <i>In Vitro<\/i>\n            Potency against Candida Species"],"prefix":"10.1128","volume":"56","author":[{"given":"Dayna","family":"Ellis","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, Mississippi State University, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiten","family":"Gosai","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Mississippi State University, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Emrick","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Mississippi State University, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Heintz","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Mississippi State University, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lanette","family":"Romans","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Mississippi State University, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna","family":"Gordon","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Mississippi State University, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-En","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Molecular Biology, Entomology and Plant Pathology, Mississippi State University, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Austin","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Department of Pathobiology and Population Medicine, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Texas A&amp;M University, College Station, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1093\/jac\/dki473","article-title":"Fluconazole for the management of invasive candidiasis: where do we stand after 15 years","volume":"57","author":"Charlier C","year":"2006","unstructured":"CharlierC. 2006. 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