{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:18:34Z","timestamp":1791199114120,"version":"4.1.0"},"reference-count":31,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2012,1]]},"abstract":"ABSTRACT<\/jats:title>\n \n An experiment was conducted in animal facilities to compare the impacts of four avian colibacillosis treatments\u2014oxytetracycline (OTC), trimethoprim-sulfadimethoxine (SXT), amoxicillin (AMX), or enrofloxacin (ENR)\u2014on the susceptibility of\n Escherichia coli<\/jats:named-content>\n in broiler intestinal tracts. Birds were first orally inoculated with rifampin-resistant\n E. coli<\/jats:named-content>\n strains bearing plasmid genes conferring resistance to fluoroquinolones (\n qnr<\/jats:italic>\n ), cephalosporins (\n bla<\/jats:italic>\n CTX-M<\/jats:sub>\n or\n bla<\/jats:italic>\n FOX<\/jats:sub>\n ), trimethoprim-sulfonamides, aminoglycosides, or tetracyclines. Feces samples were collected before, during, and after antimicrobial treatments. The susceptibilities of\n E. coli<\/jats:named-content>\n strains were studied, and resistance gene transfer was analyzed. An increase in the tetracycline-resistant\n E. coli<\/jats:named-content>\n population was observed only in OTC-treated birds, whereas multiresistant\n E. coli<\/jats:named-content>\n was detected in the dominant\n E. coli<\/jats:named-content>\n populations of SXT-, AMX-, or ENR-treated birds. Most multiresistant\n E. coli<\/jats:named-content>\n strains were susceptible to rifampin and exhibited various pulsed-field gel electrophoresis profiles, suggesting the transfer of one of the multiresistance plasmids from the inoculated strains to other\n E. coli<\/jats:named-content>\n strains in the intestinal tract. In conclusion, this study clearly illustrates how, in\n E. coli<\/jats:named-content>\n , \u201cold\u201d antimicrobials may coselect antimicrobial resistance to recent and critical molecules.\n <\/jats:p>","DOI":"10.1128\/aac.05617-11","type":"journal-article","created":{"date-parts":[[2011,10,11]],"date-time":"2011-10-11T05:29:43Z","timestamp":1318310983000},"page":"189-196","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":33,"title":["Resistance Gene Transfer during Treatments for Experimental Avian Colibacillosis"],"prefix":"10.1128","volume":"56","author":[{"given":"Alexandra","family":"Dheilly","sequence":"first","affiliation":[{"name":"ANSES, Laboratoire de Ploufragan, Unit\u00e9 Mycoplasmologie Bact\u00e9riologie, Ploufragan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"La\u00ebtitia","family":"Le Devendec","sequence":"additional","affiliation":[{"name":"ANSES, Laboratoire de Ploufragan, Unit\u00e9 Mycoplasmologie Bact\u00e9riologie, Ploufragan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwena\u00eblle","family":"Mourand","sequence":"additional","affiliation":[{"name":"ANSES, Laboratoire de Ploufragan, Unit\u00e9 Mycoplasmologie Bact\u00e9riologie, Ploufragan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axelle","family":"Bouder","sequence":"additional","affiliation":[{"name":"ANSES, Laboratoire de Ploufragan, Unit\u00e9 Mycoplasmologie Bact\u00e9riologie, Ploufragan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Jouy","sequence":"additional","affiliation":[{"name":"ANSES, Laboratoire de Ploufragan, Unit\u00e9 Mycoplasmologie Bact\u00e9riologie, Ploufragan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Kempf","sequence":"additional","affiliation":[{"name":"ANSES, Laboratoire de Ploufragan, Unit\u00e9 Mycoplasmologie Bact\u00e9riologie, Ploufragan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","unstructured":"Agence Fran\u00e7aise de S\u00e9curit\u00e9 Sanitaire des Aliments. 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