{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T21:40:45Z","timestamp":1700516445387},"reference-count":0,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[1978,4,1]],"date-time":"1978-04-01T00:00:00Z","timestamp":260236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1978,4]]},"abstract":"<jats:p>\n            Multiply drug-resistant strains of\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            were isolated from pediatric patients with severe staphylococcal infections in 1974 through 1976. Resistance to benzylpenicillin, erythromycin, and kanamycin was jointly eliminated without exception from these multiply drug-resistant strains by treatment with ethidium bromide. It was also found that the triple drug resistance in a representative strain, TK512-200, was always transduced to a susceptible strain simultaneously. Moreover, a single class of plasmid deoxyribonucleic acid was isolated from a transductant and found to be 14.4 \u00b1 0.6 \u03bcm in length, with a molecular weight corresponding to 29.8 \u00d7 10\n            <jats:sup>6<\/jats:sup>\n            . From these results, it is concluded that the plasmid (pTU512) is a new one, mediating resistance to penicillin, erythromycin, and kanamycin.\n          <\/jats:p>","DOI":"10.1128\/aac.13.4.691","type":"journal-article","created":{"date-parts":[[2012,6,27]],"date-time":"2012-06-27T23:57:02Z","timestamp":1340841422000},"page":"691-694","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":6,"title":["New Plasmid (pTU512), Mediating Resistance to Penicillin, Erythromycin, and Kanamycin, from Clinical Isolates of\n            <i>Staphylococcus aureus<\/i>"],"prefix":"10.1128","volume":"13","author":[{"given":"Megumi","family":"Kono","sequence":"first","affiliation":[{"name":"Department of Microbiology, Tokyo College of Pharmacy, 1432-1 Horinouchi, Hachioji-City, Tokyo 192-03, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Sasatsu","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Tokyo College of Pharmacy, 1432-1 Horinouchi, Hachioji-City, Tokyo 192-03, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimiko","family":"Ubukata","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medicine, Teikyo University, Kaga 2-11-1, Itabashi-ku, Tokyo 173, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Konno","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medicine, Teikyo University, Kaga 2-11-1, Itabashi-ku, Tokyo 173, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhochi","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medicine, Teikyo University, Kaga 2-11-1, Itabashi-ku, Tokyo 173, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.13.4.691","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.13.4.691","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T14:02:58Z","timestamp":1645452178000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.13.4.691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,4]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1978,4]]}},"alternative-id":["10.1128\/AAC.13.4.691"],"URL":"https:\/\/doi.org\/10.1128\/aac.13.4.691","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,4]]},"assertion":[{"value":"1978-04-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}