{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:09:12Z","timestamp":1761059352883},"reference-count":0,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[1978,12,1]],"date-time":"1978-12-01T00:00:00Z","timestamp":281318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1978,12]]},"abstract":"<jats:p>\n            The minimal inhibitory concentrations of piperacillin and seven other betalactam antibiotics were determined against 407 bacterial isolates. Piperacillin was found to be more active than ampicillin against susceptible gram-negative bacilli and more active than either carbenicillin or ticarcillin against\n            <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n            and streptococci. Although piperacillin was active against\n            <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n            , this activity was less than that of the cephalosporins. Piperacillin was not active against penicillin-resistant\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            and\n            <jats:italic>Enterobacteriaceae<\/jats:italic>\n            that were resistant to the other test antibiotics.\n          <\/jats:p>","DOI":"10.1128\/aac.14.6.919","type":"journal-article","created":{"date-parts":[[2012,6,27]],"date-time":"2012-06-27T23:57:02Z","timestamp":1340841422000},"page":"919-921","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Comparative Evaluation of Piperacillin in Vitro"],"prefix":"10.1128","volume":"14","author":[{"given":"Gordon M.","family":"Dickinson","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Miami School of Medicine, Miami, Florida 33152"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J.","family":"Cleary","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Miami School of Medicine, Miami, Florida 33152"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Hoffman","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, University of Miami School of Medicine, Miami, Florida 33152"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.14.6.919","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.14.6.919","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T23:15:10Z","timestamp":1645485310000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.14.6.919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,12]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1978,12]]}},"alternative-id":["10.1128\/AAC.14.6.919"],"URL":"https:\/\/doi.org\/10.1128\/aac.14.6.919","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,12]]},"assertion":[{"value":"1978-12-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}