{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:46:25Z","timestamp":1773189985943,"version":"3.50.1"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[1979,2,1]],"date-time":"1979-02-01T00:00:00Z","timestamp":286675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1979,2]]},"abstract":"<jats:p>\n            Three of 19 strains of\n            <jats:italic>Haemophilus ducreyi<\/jats:italic>\n            , isolated during a recent outbreak of chancroid, were found to produce \u03b2-lactamase and to harbor a 6.0 \u00d7 10\n            <jats:sup>6<\/jats:sup>\n            -dalton plasmid.\n            <jats:italic>Escherichia coli<\/jats:italic>\n            transformed with this plasmid acquired \u03b2-lactamase-mediated resistance to ampicillin. The guanine-plus-cytosine content of the plasmid was found to be 41 mol%. Restriction endonuclease digestion studies suggest that a relatively large portion of the Tn\n            <jats:italic>1<\/jats:italic>\n            translocon is carried by this plasmid. Whereas this plasmid could not be transferred to\n            <jats:italic>H. influenzae<\/jats:italic>\n            by mating on membrane filters, a strain of\n            <jats:italic>H. ducreyi<\/jats:italic>\n            was able to receive and donate a 30 \u00d7 10\n            <jats:sup>6<\/jats:sup>\n            -dalton ampicillin resistance plasmid from\n            <jats:italic>H. influenzae<\/jats:italic>\n            . The ability of\n            <jats:italic>H. ducreyi<\/jats:italic>\n            to receive and donate conjugative plasmids may result in the appearance of multiply resistant strains.\n          <\/jats:p>","DOI":"10.1128\/aac.15.2.294","type":"journal-article","created":{"date-parts":[[2012,6,27]],"date-time":"2012-06-27T23:57:02Z","timestamp":1340841422000},"page":"294-299","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":43,"title":["Plasmid-Mediated Ampicillin Resistance in\n            <i>Haemophilus ducreyi<\/i>"],"prefix":"10.1128","volume":"15","author":[{"given":"James L.","family":"Brunton","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada R3E OZ3"},{"name":"Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada R3E OZ3"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Maclean","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada R3E OZ3"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan R.","family":"Ronald","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada R3E OZ3"},{"name":"Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada R3E OZ3"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William L.","family":"Albritton","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada R3E OZ3"},{"name":"Department of Pediatrics, University of Manitoba, Winnipeg, Manitoba, Canada R3E OZ3"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.15.2.294","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.15.2.294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T23:16:09Z","timestamp":1645485369000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.15.2.294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1979,2]]}},"alternative-id":["10.1128\/AAC.15.2.294"],"URL":"https:\/\/doi.org\/10.1128\/aac.15.2.294","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,2]]},"assertion":[{"value":"1979-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}