{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T01:41:18Z","timestamp":1768009278449,"version":"3.49.0"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[1973,6,1]],"date-time":"1973-06-01T00:00:00Z","timestamp":107740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1973,6]]},"abstract":"<jats:p>\n            Axenomycins are a new group of macrolide antibiotics isolated from the fermentation broth of\n            <jats:italic>Streptomyces lisandri<\/jats:italic>\n            n.sp. They exhibit anthelmintic activity against tapeworms (\n            <jats:italic>Cestoda<\/jats:italic>\n            ). Three different fractions, A, B, and D, have been obtained, the most active fraction being axenomycin D. The activities of the axenomycin complex and axenomycin D against\n            <jats:italic>Hymenolepis nana<\/jats:italic>\n            in mice,\n            <jats:italic>Taenia pisiformis, Dipylidium caninum<\/jats:italic>\n            , and\n            <jats:italic>Diphyllobothrium<\/jats:italic>\n            sp. in dogs, and\n            <jats:italic>Moniezia expansa, M. benedeni<\/jats:italic>\n            , and\n            <jats:italic>Avitellina centripunctata<\/jats:italic>\n            in lambs were studied in experimentally and naturally infected animals. Axenomycins were effective and well tolerated by the oral route. Worm reduction rates after a single oral dose were 90 to 100% with 5 to 10 mg of axenomycin D\/kg and 50 to 100% with 20 mg of axenomycin complex\/kg.\n          <\/jats:p>","DOI":"10.1128\/aac.3.6.708","type":"journal-article","created":{"date-parts":[[2012,6,27]],"date-time":"2012-06-27T23:57:02Z","timestamp":1340841422000},"page":"708-710","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":24,"title":["Axenomycins, New Cestocidal Antibiotics"],"prefix":"10.1128","volume":"3","author":[{"given":"C. Della","family":"Bruna","sequence":"first","affiliation":[{"name":"Farmitalia, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. L.","family":"Ricciardi","sequence":"additional","affiliation":[{"name":"Farmitalia, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Sanfilippo","sequence":"additional","affiliation":[{"name":"Farmitalia, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.3.6.708","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.3.6.708","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T13:41:38Z","timestamp":1645450898000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.3.6.708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1973,6]]}},"alternative-id":["10.1128\/AAC.3.6.708"],"URL":"https:\/\/doi.org\/10.1128\/aac.3.6.708","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,6]]},"assertion":[{"value":"1973-06-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}