{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:00:04Z","timestamp":1784192404954,"version":"3.55.0"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[1989,2,1]],"date-time":"1989-02-01T00:00:00Z","timestamp":602294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1989,2]]},"abstract":"<jats:p>We evaluated the in vitro antibiotic susceptibilities of 31 coagulase-negative Staphylococcus isolates causing septicemia in neutropenic patients undergoing norfloxacin prophylaxis. All the strains but one were resistant to 1 microgram of norfloxacin per ml. At the same concentration, ciprofloxacin, ofloxacin, imipenem, and pefloxacin were inhibitory for 19 (61%), 19 (61%), 18 (58%), and 14 (45%) of the evaluated strains, respectively. Imipenem had an MBC\/MIC ratio of greater than or equal to 32 against 19 (61%) of the evaluated isolates, and resistant subpopulations were detected at 5 micrograms\/ml in 16 of 17 oxacillin-resistant strains and in 3 of 14 oxacillin-susceptible or -tolerant strains. Resistance to gentamicin was seen with increased frequency among slime-producing strains.<\/jats:p>","DOI":"10.1128\/aac.33.2.209","type":"journal-article","created":{"date-parts":[[2012,6,28]],"date-time":"2012-06-28T00:04:52Z","timestamp":1340841892000},"page":"209-211","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":23,"title":["Comparative in vitro activities of new fluorinated quinolones and other antibiotics against coagulase-negative Staphylococcus blood isolates from neutropenic patients, and relationship between susceptibility and slime production"],"prefix":"10.1128","volume":"33","author":[{"given":"M","family":"Venditti","sequence":"first","affiliation":[{"name":"Cattedra di Patologia Medica III, Universit\u00e0 di Roma, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Santini","sequence":"additional","affiliation":[{"name":"Cattedra di Patologia Medica III, Universit\u00e0 di Roma, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Serra","sequence":"additional","affiliation":[{"name":"Cattedra di Patologia Medica III, Universit\u00e0 di Roma, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Micozzi","sequence":"additional","affiliation":[{"name":"Cattedra di Patologia Medica III, Universit\u00e0 di Roma, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Gentile","sequence":"additional","affiliation":[{"name":"Cattedra di Patologia Medica III, Universit\u00e0 di Roma, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Martino","sequence":"additional","affiliation":[{"name":"Cattedra di Patologia Medica III, Universit\u00e0 di Roma, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.33.2.209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.33.2.209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T15:07:57Z","timestamp":1645456077000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.33.2.209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1989,2]]}},"alternative-id":["10.1128\/AAC.33.2.209"],"URL":"https:\/\/doi.org\/10.1128\/aac.33.2.209","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,2]]},"assertion":[{"value":"1989-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}