{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T20:05:46Z","timestamp":1783109146562,"version":"3.54.6"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[1992,2,1]],"date-time":"1992-02-01T00:00:00Z","timestamp":696902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1992,2]]},"abstract":"<jats:p>Antibiotic susceptibility surveillance testing was performed on clinical isolates of Neisseria gonorrhoeae collected in September 1989 in the Philippines. beta-Lactamase was produced by 77 (55%) of 140 isolates. In vitro MIC testing revealed significant resistance to penicillin (MIC for 90% of isolates [MIC90], greater than 64 micrograms\/ml), tetracycline (MIC90, 4 micrograms\/ml), and cefmetazole (MIC90, 8 micrograms\/ml). Spectinomycin resistance was rare (10 of 117), but the MIC90 was 32 micrograms\/ml. Isolates were susceptible to fluoroquinolones and cephalosporins at the time of this survey, as evidenced by the MIC90s of ciprofloxacin (0.25 microgram\/ml), norfloxacin (2.0 micrograms\/ml), ofloxacin (0.625 microgram\/ml), cefpodoxime (2.0 micrograms\/ml), cefotaxime (1.0 microgram\/ml), ceftazidime (0.25 microgram\/ml), ceftizoxime (0.25 microgram\/ml), and ceftriaxone (0.06 microgram\/ml). To date, ceftriaxone resistance has not emerged, despite the widespread use of this antibiotic in the Philippines.<\/jats:p>","DOI":"10.1128\/aac.36.2.277","type":"journal-article","created":{"date-parts":[[2012,6,28]],"date-time":"2012-06-28T00:05:50Z","timestamp":1340841950000},"page":"277-282","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":41,"title":["In vitro antibiotic susceptibilities of Neisseria gonorrhoeae isolates in the Philippines"],"prefix":"10.1128","volume":"36","author":[{"suffix":"3rd","given":"T E","family":"Clendennen","sequence":"first","affiliation":[{"name":"Navy Environmental and Preventive Medicine Unit Six, Pearl Harbor, Hawaii 96860-5040."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C S","family":"Hames","sequence":"additional","affiliation":[{"name":"Navy Environmental and Preventive Medicine Unit Six, Pearl Harbor, Hawaii 96860-5040."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E S","family":"Kees","sequence":"additional","affiliation":[{"name":"Navy Environmental and Preventive Medicine Unit Six, Pearl Harbor, Hawaii 96860-5040."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F C","family":"Price","sequence":"additional","affiliation":[{"name":"Navy Environmental and Preventive Medicine Unit Six, Pearl Harbor, Hawaii 96860-5040."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W J","family":"Rueppel","sequence":"additional","affiliation":[{"name":"Navy Environmental and Preventive Medicine Unit Six, Pearl Harbor, Hawaii 96860-5040."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A B","family":"Andrada","sequence":"additional","affiliation":[{"name":"Navy Environmental and Preventive Medicine Unit Six, Pearl Harbor, Hawaii 96860-5040."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G E","family":"Espinosa","sequence":"additional","affiliation":[{"name":"Navy Environmental and Preventive Medicine Unit Six, Pearl Harbor, Hawaii 96860-5040."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Kabrerra","sequence":"additional","affiliation":[{"name":"Navy Environmental and Preventive Medicine Unit Six, Pearl Harbor, Hawaii 96860-5040."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F S","family":"Wignall","sequence":"additional","affiliation":[{"name":"Navy Environmental and Preventive Medicine Unit Six, Pearl Harbor, Hawaii 96860-5040."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.36.2.277","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.36.2.277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T15:22:09Z","timestamp":1645456929000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.36.2.277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992,2]]}},"alternative-id":["10.1128\/AAC.36.2.277"],"URL":"https:\/\/doi.org\/10.1128\/aac.36.2.277","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,2]]},"assertion":[{"value":"1992-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}