{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:47:17Z","timestamp":1790689637987,"version":"4.1.0"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[1993,5,1]],"date-time":"1993-05-01T00:00:00Z","timestamp":736214400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1993,5]]},"abstract":"<jats:p>Eighteen children with bacteriologically confirmed severe typhoid fever were initially treated intravenously with ciprofloxacin (10 mg\/kg of body weight per day). Clinical cure with eradication of multiresistant Salmonella typhi infection was observed in 17 patients (94.4%; 95% confidence interval [CI], 84 to 100%). Children regained normal consciousness within an average of 2 days (95% CI, 1.8 to 2.2 days). The temperatures of the children returned to normal within 3.3 days (95% CI, 3.1 to 3.5 days). Complications were not observed during the hospital stay or a 3-month follow-up period. Relapse and carrier state were also not encountered during the follow-up period.<\/jats:p>","DOI":"10.1128\/aac.37.5.1197","type":"journal-article","created":{"date-parts":[[2012,6,28]],"date-time":"2012-06-28T00:05:50Z","timestamp":1340841950000},"page":"1197-1199","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":58,"title":["Ciprofloxacin for treatment of severe typhoid fever in children"],"prefix":"10.1128","volume":"37","author":[{"given":"P","family":"Dutta","sequence":"first","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Calcutta, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Rasaily","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Calcutta, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M R","family":"Saha","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Calcutta, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U","family":"Mitra","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Calcutta, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S K","family":"Bhattacharya","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Calcutta, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M K","family":"Bhattacharya","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Calcutta, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Lahiri","sequence":"additional","affiliation":[{"name":"National Institute of Cholera and Enteric Diseases, Calcutta, India."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.37.5.1197","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.37.5.1197","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T15:34:00Z","timestamp":1645457640000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.37.5.1197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,5]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1993,5]]}},"alternative-id":["10.1128\/AAC.37.5.1197"],"URL":"https:\/\/doi.org\/10.1128\/aac.37.5.1197","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,5]]},"assertion":[{"value":"1993-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}