{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T18:15:14Z","timestamp":1789928114265,"version":"4.0.1"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[1973,9,1]],"date-time":"1973-09-01T00:00:00Z","timestamp":115689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1973,9]]},"abstract":"<jats:p>\n            The genetic basis for resistance to a number of antibiotics was examined in\n            <jats:italic>Rhizobium japonicum<\/jats:italic>\n            . Resistance to penicillin G, neomycin, and chloramphenicol appears to be mediated by an extrachromosomal element similar to that found in the\n            <jats:italic>Enterobacteriaceae<\/jats:italic>\n            . Resistance to these antibiotics was eliminated from cells by treatment with acridine orange, and resistance to all three antibiotics could be transferred en bloc to\n            <jats:italic>Agrobacterium tumefaciens<\/jats:italic>\n            under conditions excluding transformation or transduction as possible genetic mechanisms.\n          <\/jats:p>","DOI":"10.1128\/aac.4.3.248","type":"journal-article","created":{"date-parts":[[2012,6,27]],"date-time":"2012-06-27T23:57:02Z","timestamp":1340841422000},"page":"248-253","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":239,"title":["Transmissible Resistance to Penicillin G, Neomycin, and Chloramphenicol in\n            <i>Rhizobium japonicum<\/i>"],"prefix":"10.1128","volume":"4","author":[{"given":"Michael A.","family":"Cole","sequence":"first","affiliation":[{"name":"Department of Microbiology, North Carolina State University, Raleigh, North Carolina 27607"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald H.","family":"Elkan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, North Carolina State University, Raleigh, North Carolina 27607"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.4.3.248","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.4.3.248","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T23:10:52Z","timestamp":1645485052000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.4.3.248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,9]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1973,9]]}},"alternative-id":["10.1128\/AAC.4.3.248"],"URL":"https:\/\/doi.org\/10.1128\/aac.4.3.248","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,9]]},"assertion":[{"value":"1973-09-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}