{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T15:03:19Z","timestamp":1761663799845},"reference-count":15,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[1998,10,1]],"date-time":"1998-10-01T00:00:00Z","timestamp":907200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[1998,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Two strains of\n            <jats:italic>Streptococcus pneumoniae<\/jats:italic>\n            isolated from sputum and bronchoalveolar samples with high-level resistance to cefotaxime (MIC = 8 to 16 \u03bcg\/ml) are described. One of them, belonging to serogroup 19, was also highly resistant to penicillin (MIC = 16 \u03bcg\/ml), while the other, of serogroup 14, was intermediate in its resistance to penicillin (MIC = 0.25 \u03bcg\/ml). To our knowledge, these are the first two strains to be isolated in Spain with such high levels of resistance to cefotaxime.\n          <\/jats:p>","DOI":"10.1128\/aac.42.10.2768","type":"journal-article","created":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T00:29:31Z","timestamp":1539044971000},"page":"2768-2769","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":9,"title":["Description of Two New Isolates of\n            <i>Streptococcus pneumoniae<\/i>\n            in Spain That Are Highly Resistant to Cefotaxime"],"prefix":"10.1128","volume":"42","author":[{"given":"Joaqui\u0301n","family":"Ruiz","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Seccio\u0301n de Microbiolog\u0131\u0301a, Hospital Universitario Virgen de la Arrixaca, El Palmar 30120, Murcia,1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Sempere","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2-->Laboratorio de Ana\u0301lisis Cl\u0131\u0301nicos, Hospital Costa del Sol, Marbella, Ma\u0301laga,2 and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Encarnacio\u0301n","family":"Simarro","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Seccio\u0301n de Microbiolog\u0131\u0301a, Hospital Universitario Virgen de la Arrixaca, El Palmar 30120, Murcia,1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asuncio\u0301n","family":"Fenoll","sequence":"additional","affiliation":[{"name":"<!--label omitted: 3-->Centro Nacional de Microbiolog\u0131\u0301a, Majadahonda 28220, Madrid,3 Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199111000-00018"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/18.5.766"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.39.6.1306"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.1995.1.29"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0966-842X(94)90612-2"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.36.4.886"},{"key":"e_1_3_1_8_2","unstructured":"Goldstein\n              F. W.\n              Li\u00f1ares\n              J.\n              Melo Cristino\n              J.\n              Malafiiej\n              E.\n              Marcova\n              M.\n              Marton\n              A.\n              Murphy\n              J.\n              Schito\n              G.\n              Trupl\n              Y.\n              Urbascova\n              P.\n              Vanhoof\n              R.\n            the European Study Group Hospital Saint Joseph Paris\n          Comparison of the intrinsic activity of 9 betalactams (BL) against 1131 strains of Streptococcus pneumoniae (S.p.) isolated in the 11 European countries between 1993 and 1995 abstr. T148.\n          Program and abstracts of the First European Congress of Antimicrobial Chemotherapy Glasgow Scotland\n          1996"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.17.3.364"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199503303321317"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/163.3.542"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1992.tb01422.x"},{"key":"e_1_3_1_13_2","unstructured":"National Committee for Clinical Laboratory Standards\n          Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically\n          4th ed. Approved standard M7-A4\n          1997\n          National Committee for Clinical Laboratory Standards\n          Wayne Pa"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/171.6.1491"},{"key":"e_1_3_1_15_2","first-page":"662","article-title":"Cephalosporin treatment failure in penicillin-resistant and cephalosporin-resistant Streptococcus pneumoniae meningitis.","volume":"11","author":"Sloas M. M.","year":"1992","unstructured":"Sloas M. M. Barrett F. F. Chesney P. J. English B. K. Hill B. C. Tenover F. C. Leggiadro R. J. Cephalosporin treatment failure in penicillin-resistant and cephalosporin-resistant Streptococcus pneumoniae meningitis. Pediatr. Infect. Dis. J. 11 1992 662 666","journal-title":"Pediatr. Infect. Dis. J."},{"key":"e_1_3_1_16_2","unstructured":"Thornsberry\n              C.\n              Burton\n              P. H.\n              Vanderhoof\n              B. H.\n          Increasing resistance to third-generation cephalosporins in Streptococcus pneumoniae : a 1995 surveillance study in the United States abstr. LB-24.\n          Program addendum of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy.\n          1995\n          American Society for Microbiology\n          Washington D.C"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.42.10.2768","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.42.10.2768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T15:38:28Z","timestamp":1645457908000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.42.10.2768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,10]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1998,10]]}},"alternative-id":["10.1128\/AAC.42.10.2768"],"URL":"https:\/\/doi.org\/10.1128\/aac.42.10.2768","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,10]]},"assertion":[{"value":"1998-02-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1998-08-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1998-10-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}